• Skyemberr's Avatar

    Skyemberr asked a questionColorectal (Colon) Cancer

    Too many steroids and blood sugar

    8 answers
    • carm's Avatar
      carm

      @Skyemberr,
      I totally get it when it comes to the dex. But when you talk to the doctor, ask for the tapering schedule that you should expect. I think that you won't be on one dose all the way through. Good policy for any steroid, especially dex, is to taper down the dose before you come off entirely. It does have it's down side, but it is very successful at decreasing the swelling. It can also be a benefit while on FOLFIRI. Dex tends to help ease nausea, and believe it or not, it also causes a significant increase in proliferation and activation of regulatory T cells. This helps the bodys' immune system to fight cancer during times when you select your WBC counts to drop. Rapid reproduction of T cells is always a benefit in this setting. Best of luck to you, Carm.

      about 18 hours ago
    • cards7up's Avatar
      cards7up

      How long ago did you have SBRT? Normally they start higher and reduce the dosage within a short amount of time. I'd ask about reducing the dosage. Good luck!

      about 10 hours ago
    • Skyemberr's Avatar
      Skyemberr

      @cards7up I had SBRT in 5 fractions. It's all done. They are just countering pre existing swelling I have in the brain from the mass. When they start to taper down I'm having very odd effects that make them think there is a lot of pressure on the brain.

      @carm We are on a taper down schedule, but I keep having reactions so I get tapered down for a day or two and then they raise it back up. I'm happy to say I'm finally down to 8mg a day now for the last 3 days. The latest taper down schedule is pretty slow with it ten days before I step down 2mg each time. I have 3 different oncologists messing with the taper so I'm not sure if they will leave it alone, though I'm sure I'll stay on it for awhile.

      I'll take your and @JaneA advice on Tuesday and talk with my infusion oncologist about metformin. That's great to know that it increases efficacy! I want to go as hard as I can on these next 3 rounds and really kick this cancer in the butt!!

      Thank you so much for your time and advice!

      about 6 hours ago
  • Skyemberr's Avatar

    Skyemberr asked a questionColorectal (Colon) Cancer

    Cancer Research Institute

    6 answers
    • lo15's Avatar
      lo15

      I do not have experience with that facility but my husband is in a trial at DF and he also has a navigator and a PA from the trial at every appointment in addition to his normal Dr. We had numerous appointments with different Doctors, tests, questionnaire's etc. Been on it for two months, let you know next month what the thoughts are. He feels very sick since he has been on it but all the side effects are from one of the meds being giving. His opinion on it is, he is healthy enough to be in the study , who knows how long that will last, lets go for it!!

      2 months ago
    • NoLiver's Avatar
      NoLiver

      I have studied the trials, where they are available, and what studies I might be able to qualify for, just in case my 1st line of defense fails. I hope I don't have to use a trial, but on the other hand it's nice to know that there is sort of a safety net in case.

      2 months ago
    • Skyemberr's Avatar
      Skyemberr

      Yes, I'm happy to know someone is out there giving group invites to trial info because it seems like patients are almost left on their own to find trials sometimes.

      I'm happy to hear all of this positive info about CRI. I'll let you guys know if I find out anything interesting, and likewise will mention whatnext.com if I get a chance and am talking to the right person!

      2 months ago