• About Lung Cancer and mutation testing

    Asked by CAS1 on Wednesday, February 27, 2013

    About Lung Cancer and mutation testing

    I have suggested to folks with Lung Cancer the importance of Mutation testing because of the targeted therapy available. "Lets test now" is one resource. Cancer grace is another for sound lung cancer info. And below is a link to an article from MSK ( No.1 cancer center in the world) about targeted treatment available. And the data from a mutation test helps all cancer reserch so its important for all of us. It breaks my heart to see folks who are not being tested because there may be additional options available.

    I am EGFR positive so if my cancer returns I might be helped for a long time, maybe years, by EGFR inhibitors.

    Also anyone can set up a google alert based upon any subjects you choose which will bring you the daily publications to your email box like your cancer information.


    Dear Greg, maybe we could have an option called Info.

    2 Answers from the Community

    • CherylS@StF's Avatar

      I absolutely agree with you regarding the importance of Mutation testing. At St. Francis Hospital our Oncology physicians include Mutation testing for certain type lung cancers as part of the routine workup. Even when a patient has had surgery and post operatively fall into the observation category the Mutation testing is ordered in case the patient recurs and that way if the patient should need further treatment we already have the results as to whether they have the mutation. A part of the patients workup for Lung lab orders include EGFR/ALK/VerisStrat when the pathology is appropriate. While only a small percentage of patients actually do end of having the mutation, if you are one of the patients in that small percentage how awesome is that! Make sure you be proactive and ask your oncologist if your lung cancer histology is one that should have Mutation testing ordered. It is important that patients and their families be educated and informed about their particular cancer diagnosis so they can advocate for themselves or their loved ones when appropriate.

      over 5 years ago
    • CAS1's Avatar

      Dear Cheryl S thank you for that support to this very important tool for lung cancer. There is a paper published from Harvard in 2011 where certain peoples mutations had changed completely during treatment and progression. I mean some went from NSCLC to SCLC and then back to NSCLC with an EGFR mutation. These changes had a HUGE impact on their treatment and survival.. I was mutation tested twice..First time No mutations..Second time with a 220 mutation sequence and we found the EGFR.
      And all this data is going into data bases that will help find the cure. Its so very important.

      over 5 years ago

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