I have taken afinitor 10mg 1 x day for 2.5 months, and I can say that my issues have been increased bowel movements ( 7 to 8 a day),not so much diareha but runny and almost chalk like coloring and the most annoying and painful is the cramping associated with the bowel movements, and I also lost 20lbs in 2 months, I just stopped taking it 7 days ago on my own just to see if there are any changes, came back down to having 2 to 3 bowel movements and gained back 4 lbs in a weeks time, have to see doctor next week and discuss other options. Let me know if you have any side effects, I would be curious to know