• Any feedback on clinicial trials? Is there anyone familiar with the Pertuzumab Clinical Trial (Aphinity)? Any participants out there?

    Asked by Zappy on Tuesday, November 20, 2012

    Any feedback on clinicial trials? Is there anyone familiar with the Pertuzumab Clinical Trial (Aphinity)? Any participants out there?

    I recently got offered to take part of this blind study. Although I've done a lot of research on this and weighted out the cons vs pros, the unknown of the long term effects can be pretty scary. However, Pertuzumab is the drug being tested that has shown to work well with Herceptin and could be an added benefit. If all goes as planned, will be starting TCH and Pertuzumab or Placebo on 11/30. TCH given every 3 weeks for a 18 week cycle.

    5 Answers from the Community

    5 answers
    • Harry's Avatar

      I don't know this drug, but it is my understanding that the American Cancer Society considers clinical trials in general to be the best treatment.

      over 8 years ago
    • carm's Avatar

      I believe that trial is sponsored by LaRoche and Genentech and is actively recruiting. If you want to know if there is any safety issues just go to the FDA website and on the home page there is a section on recalls and safety alerts, click on that and in the search bar type in the name of the drug. If there is an issue, it will be there. Good luck, Carm.

      over 8 years ago
    • Crash's Avatar

      I am alive only because I was part of a clinical trial.

      Here is a site which may provide more information about clinical trials.

      About TGen
      The Translational Genomics Research Institute (TGen) is a Phoenix, Arizona-based non-profit organization dedicated to conducting groundbreaking research with life changing results. Research at TGen is focused on helping patients with diseases such as cancer, neurological disorders and diabetes. TGen is on the cutting edge of translational research where investigators are able to unravel the genetic components of common and complex diseases. Working with collaborators in the scientific and medical communities, TGen believes it can make a substantial contribution to the efficiency and effectiveness of the translational process. TGen is affiliated with the Van Andel Research Institute in Grand Rapids, Michigan. For more information, visit: www.tgen.org.

      Buona fortuna!

      over 8 years ago
    • Harry's Avatar

      Here is an article about Pertuzumab: http://www.cancer.gov/cancertopics/druginfo/fda-pertuzumab

      over 8 years ago
    • po18guy's Avatar

      Like crash, I am also alive only because of a clinical trial. The choice in my case was easy - the other option was palliative care/hospice. Without the trial drug (which I still receive), I would not have survived 2009. Still, clinical trials are varied as to their phase and type. Here is a link to the National Institute of Health's page on clinical trials: http://www.clinicaltrials.gov/
      I would suggest reading up a bit on the types of trials, then inquiring as to which type of trial you are being presented with. Remember hat one is never locked into a trial - you may leave for any reason, and rely upon the best existing medical standard (if there is one) for your disease. Every drug that we have ever received has gone through the trial process. In a trial, we have the advantage of receiving cutting edge treatment long before the FDA gets around to approving the drug.

      over 8 years ago

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