• Are there any treatments using stem cells

    Asked by FLymphoma18 on Friday, April 19, 2019

    Are there any treatments using stem cells

    3 Answers from the Community

    • po18guy's Avatar

      Can you be a bit more specific? "Stem cells" relates to immature cells produced in the bone marrow. They are involved in the two major classes of stem cell transplants: autologous and allogeneic. Autologous transplants use your own cells, which are harvested and re-introduced to your bloodstream after your marrow/immune system has been neutralized. Allogeneic transplants use blood stem cells from a donor, whether related to you or not, again after your original immune system has been neutralized or eliminated.

      Is doctor proposing a stem cell transplant in your case?

      about 1 year ago
    • FLymphoma18's Avatar

      I was not proposed anything related to this I have been hearing so much about how this can held people with knee and hip pain. Just wondering. because they are talking about going to start chemo and I hate that idea.

      about 1 year ago
    • po18guy's Avatar

      Oh, that would probably be an allogeneic stem cell transplant in cases of serious auto-immune disease. There are many auto-immune diseases and conditions (from Psoriasis to Lupus to Rheumatoid Arthritis) which involve the patient's own immune system attacking healthy cells. The reasons for this are not completely understood.


      However, prior to such a radical procedure as a stem cell transplant, there are many new drugs in the "inhibitor" class which regulate one's own immune system so as to reduce or eliminate the body's attack on itself. I would think that it is prudent to try the various immune modulating drugs before undergoing a transplant.

      As to chemotherapy, there is far less to fear these days than even in the recent past. New drugs have entered the market at a steady rate and non-chemo "biological" drugs are gaining popularity. In cases of follicular lymphoma, the standard is often some modification of the age-old CHOP regimen used against lymphoma. Commonly, the new drug Rituxan is added, to make R-CHOP.

      On occasion, a substantially different variation is administered. It is known as B-R, for Bendamustine plus Rituxan. Both regimens are generally far superior to th "old guard" chemo regimens.

      Oh, and as to chemo, since August 2008, I have received 20 drugs in something like 11 or 12 regimens, 19 of those drugs anti-cancer - either chemotherapy of biological. Add to that full body irradiation and an allogeneic stem cell transplant. I am still here, and delighted to be anywhere at all.

      about 1 year ago

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