• Avastin Clinical Trial

    Asked by rjtom on Saturday, March 30, 2013

    Avastin Clinical Trial

    I have just finished doing a clinical trial for a drug called Avastin. I have been experiencing major muscular and joint pain in my legs. Has anyone else had this type of trouble? It has been very frustrating and I'm told it shouldn't be a side effect yet here I am having this trouble.

    8 Answers from the Community

    8 answers
    • SueRae1's Avatar
      SueRae1

      rjtom, long story short, yes. I was on Avistan from May of last year through Jan 10 of this year. It was one of the drugs in both of my cocktails as it is used to treat both TNBC and Kidney Cancer. My upper and lower leg muscles became tight and painful, as well as issues with my knees. Everyone is unique, and everyone manifests different side effects and the onset and severity are unique to the individual.

      about 4 years ago
    • Vjp2012's Avatar
      Vjp2012

      I am currently in an Avastin trial. Had first dose 3/21/13. I have muscular and joint pain too in knees, legs, and hands. I was told it is a side effect. But, the taxol I get with it also causes the pain. I have to use ice packs wrapped around both legs to sleep at night. I was also told by my oncologist and kind people from this site to take Claritin in the morning and Benadryl at night. It helps, but ask your doctor first. Good luck!

      about 4 years ago
    • c25862's Avatar
      c25862

      I took avastin as well but I didn't have any side effects. My doctor did tell me that joint pain was a side effect. I sorry to hear this has happened to you. I pray that you get better :)

      about 4 years ago
    • fuzzylinux's Avatar
      fuzzylinux

      They added Avastin (Bevacizumab) to my FOLFIRI infusions Jan 2013. No muscle pain but a slight increase in headaches, tooth and gum pain, a pimple type rash on my face and scalp, constipation rather than diarrhea, dizziness and weakness increased as well as fatigue. Just coming to the sixth cycle (Tuesday) of it and time for my 3 month CT scan and oncologist visit (April 8). I usually get a break from chemo at the 3 month points of a couple weeks and will look forward to that.

      Mike D.

      about 4 years ago
    • SpunkyS's Avatar
      SpunkyS

      Yes, I am currently on it as a clinical trial too.I have been on it as part of my chemo Feb - June, 2012, and then just Avastin since mid June, 2012. I had a few times post infusion where my major joints ached. That is not a problem anymore, although my hands tend to ache and be stiff the week after infusion.
      I take 1 ibuprofen twice a day. It helps. If I forget it, I can feel it.

      about 4 years ago
    • Chrislora's Avatar
      Chrislora

      Hello, My wife has started using Avastin during her 2nd chemo cycle. She has been experiencing abdonminal pain off and on. But not sure its related to the drug. She has only had the pain a few days She is also using oxalifplatin and 5FU during her treatment. No major joint pain.

      about 4 years ago
    • Chrislora's Avatar
      Chrislora

      Hello again. My wifes major side effects have been weakness, fatigue, loss of muscle mass, swollen ankles a few days after the chemo application. Some slight diarrhea. Sensitive to cold surfaces. We r praying for you. We will BEAT THIS:).

      about 4 years ago
    • SpunkyS's Avatar
      SpunkyS

      Must have been the power of suggestion. After posting that I did not have too much of a bad time, I had my Avastin infusion this week and bam, my shoulder and knee joints hurt like crazy!
      Also very annoyed by runny nose - - faucet turned on full force runny. That settles down to a slow drip after a few days so I forget about it. Time to check with MD about something to slow it down.

      about 4 years ago

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