• Son's Avatar

    CARBOplatin and PACLitaxel Chemo

    Asked by Son on Wednesday, March 20, 2013

    CARBOplatin and PACLitaxel Chemo

    The doctor is suggesting doing chemo in 2 days. One day for each medicine. The protocols I have researched on the internet suggest that they can be done on the same day. Are there any benefits/drawbacks in doing them separately?

    5 Answers from the Community

    5 answers
    • CAS1's Avatar

      Perhaps time..If you have not had either chemo before, and since they are both platinums they will go slow to ensure you do not have a reaction. A one day difference should not have any impact on its efectiveness in your body.

      over 3 years ago
    • Becky@UMich's Avatar
      Becky@UMich RN, BS, OCN, Cancer AnswerLine Nurse

      A great question- hope this answer helps! Carboplatin and Paclitaxel are a chemotherapy combination often used for women with certain stages of cervical cancer. Both can cause an allergic reaction- with symptoms typically mild (fever, chills, skin itching, or feeling flushed). Some people however can experience a more severe reaction. Just to be cautious, sometimes physicians start out giving new drugs slowly especially for the first few times to see how the person tolerates the medicine. Giving these medications separately, instead of on the same day will not change/impact the effectiveness of the treatment.
      Carboplatin is given by IV over 15 to 60 minutes usually once a month. Patients regularly get an anti-nausea medication before receiving this chemotherapy. Paclitaxel is also given by IV, over various amounts of times and schedules. Most patients will take a steroid, an antihistamine and an anti-nausea medication before chemotherapy starts to lessen the chance of an allergic reaction.
      It’s important to understand that the dose and schedule for Carboplatin and Paclitaxel depends on multiple factors including the patient’s weight, organ function (for example: liver and kidney) and side effects if any they experience.
      Read more:
      Becky RN OCN

      over 3 years ago
    • SueRae1's Avatar

      One draw back is spending two days in the infusion center, instead of one. Is the doctor suggesting this for all treatments or just the first one or two. I know that the first treatments take longer because they slow the drip to monitor for side effects. My first infusion took almost 5 hours, they increased the drip time over the course of my first cycle until we got it down to 1-2 hours (for 2/3 drugs depending on the week)

      over 3 years ago
    • Son's Avatar

      Thanks everyone for answering my question. My mind is at ease now.

      over 3 years ago
    • Cindy's Avatar

      I had both on the same day when I had my chemo. They gave my the paclitaxel first very slowly over about 4 hours because it is the most toxic of the two. Then they gave me the Carboplatin faster in about 1 hour. Prior to all that, I was given several medications to counteract the side affects. I was in the doctor's office longer to get my chemo than anyone else that was doing it at the same time as I was. Several times I was the last one to leave.

      over 3 years ago

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