• Chemo after liver resection?

    Asked by mtnraindancer on Saturday, December 8, 2018

    Chemo after liver resection?

    I can't help but wonder how my body would handle "mop-up" chemo after a liver and colon resection. From what I understand, I would have my gallbladder removed as well. I would imagine my digestive system will be a wreck and take time to recover and will most definitely be "different". With such a compromised body from surgery, I really struggle with putting "chemo" back into my body. I have always been more of a "holistic" minded individual but here I am doing Avastin and Folfox, scared and fighting for my life. Has anyone had experience with chemo after a colon and liver resection? How hard did it knock you down? For every 10 studies you read suggesting something, you have another 10 against it. I realize we are all unique individuals who have to make our own decisions but it sure helps to share here and learn from those who have walked the path. Wishing everyone a beautiful day full of good things!

    4 Answers from the Community

    4 answers
    • lo15's Avatar

      Just a comment. MY husband is in the same place you are ( colon cancer with liver mets). We go to Dana Farber. They wont do anything besides chemos, etc because they say cancer is in his bloodstream, so any surgery would put him out of commission too long and away from chemo. Of course his liver mets are pretty bad so … So I was surprised to read what you wrote about surgery. Best of luck, keep us updated

      10 months ago
    • JaneA's Avatar

      I had mop-up chemo after my rectal cancer surgery - APR surgery which is a complex surgery and results in a permanent colostomy. My pathology report showed six positive lymph nodes so I had six more cycles of FOLFOX with Avastin.

      My side effects were the same as before surgery - fatigue for a few days - and diarrhea on the 4th day after infusion.

      Best wishes - don't borrow trouble - whether you have mop up chemo is usually based on the pathology report. I had a lung met and nothing in my liver. But I wanted to LIVE so I pledged to myself that I would "endure the cure."

      10 months ago
    • Kbaarch's Avatar

      I had Avastin and Xeloda for three months, eight months after colon and liver resection. It was harder than I expected (fatigue) but nothing major.
      In remission from stage 4 colon cancer.

      10 months ago
    • Skyemberr's Avatar

      I had Xeloda chemo with 29 days of radiation, then I went straight to a major surgery where I had part of my colon removed, my vaginal wall removed and replaced with a transplanted muscle taken from my chest, an appendectomy, ileostomy and anastomosis. The surgery was very hard on my body and I almost died due to the complications and infections.

      I was told I had to start FOLFOX chemo within 8 weeks of the surgery. This was tough because the incision had burst at the bottom due to infection, and I was on a wound-vac for a month trying to get that incision to close up enough.

      I dragged my heels as much as I could because I felt really under the weather and was concerned about taking a hit from the chemo so soon after the major surgery. It is a very valid concern! I started my chemo at about 10 weeks from surgery.

      I had very big complications that landed me in the hospital in between each round of folfox, even with the dosage cut in half. We found out later that part of the reason why is because my body reacts to FOLFOX as if it is a neurotoxin. That actually isn't too typical, thankfully.

      You are correct to be very concerned about how your body could react. Complications can be very serious. Then you have people like my mom who has the same cancer that I do, and is on round 11 of FOLFOX with barely any complications. Everyone is different.

      Unfortunately, at this point FOLFOX and FOLFIRI are the two most effective tools the docs have to do the mop up chemo and give you a shot at getting rid of the cancer, or at least getting it under control. I wish I had been able to continue my FOLFOX for a few more rounds, or at a full dosage because if I had there is a chance I would not be metastatic now.

      It was worth doing it even though it gave me complications and didn't end up curing me. It has still prolonged my life enough to give me a chance to wait for the study or treatment that will save me. Hopefully in your case at the very least, it will get you to NED.

      Please keep coming back in if you have questions or need support. We want to help you fight.

      10 months ago

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