Hi Whisper, I had four rounds of Taxol this past winter and the first one had me in bed for four days, writhing in pain because my body hurt so much. I have a port in my upper chest, so that's how I receive infusions, not through a shot. The pain was stabbing and 'floated' throughout my body, attacking me in my wrist, then my knees, ankles, pelvic area, back, etc. It just kept bouncing from one place to another in seconds. I twisted around like I was having seizures. Very bizarre and painful.
Oddly enough, my oncology nurses told me to take Claritin D and Alleve the day before, the day of, and the day after my Taxol treatment. That did the trick. Apparently Taxol is derived from tree bark or something like that and is loaded with histamines, so the Claritin D, which has anti-histamines in it, counteracts it. I still had some mild, but bearable, pain with that regimen. At least I wasn't stuck in bed, crying in agony.