• Does anyone have experience with the Rituxin-Bendamustine combination therapy?

    Asked by kira on Sunday, January 15, 2012

    Does anyone have experience with the Rituxin-Bendamustine combination therapy?

    My NHL was originally addressed by surgery, including removal of an extremely enlarged and dangerous spleen and some lymph nodes. It was already widespread, and now almost three years later has advanced to my lungs (lymphoma in lungs...not lung cancer). Just started treatment and wondering if others have experience with this approach

    4 Answers from the Community

    4 answers
    • ejonespw's Avatar

      I was diagnosed stage four NHL it was Is in lungs liver pancrease lymphnods said was not Operable on what they call r chop a four chemo injection every three weeks for eight treatments I have only been diagnosed for three months what have they told you did u to threw chemo before when they operated how long before it reappeared hope irony mind me askin these things mine was late stage told me disk look good at first seem to be comin around as far as I can tell no pain I was able to back to work this last week feels good to do things will Pray for u keep busy wish had answer for u

      almost 5 years ago
    • Chris' Avatar

      After 6 months of agressive chemo - I have rituxin every six months - then one month - once a week. This June will be my 4th treatment - it has done miracles for my cell b, stage 4 NHL. I have lost my thyroids and one kidney, plus they removed a lymph node in my neck prior to the maintenance treatment.

      over 4 years ago
    • Harry's Avatar

      I received rituxan+bendamustine. I had an atypical reaction to the rituxan but the bendamustine was a piece of cake. Most patients find rituxan relatively easy. I didn't but that's not a reason to avoid it. Try premedication to reduce side effects and reduce the infusion rate if necessary. In my case the reaction was too severe. But, it also knocked back my NHL (Waldenstrom's) to the point that I am not undergoing any treatment at present. If I need treatment again I will be looking at Ofatumumab as that looks like it will have even less side effects than rituxan.

      about 4 years ago
    • Tana928's Avatar

      I was diagnosed with NHL follicular B cell stage Vi in February of 2012. My spleen was also involved. Normal spleen is 11cm and mine was 32cm. Did 4 rounds of Rituxan and began to see/feel results right away. Could lay on my left side again after just the first treatment. I did have a fairly severe reaction to the Rituxan on my first infusion. Chills, lowered O2 level, heart pal patios and near seizure like shakes. This does occasionally happen on the first time, but usually does not repeat. They just stopped the infusion until I was back in control and then finished it at a slower drip rate. Rounds 2, 3, and 4 were uneventful.

      PET scan after those treatments showed marked improvement, with some nodes in my underarm and abdomen still involved.

      I was then given 8 rounds of Rituxan/Treanda(Bendamustine). Very few side effects at all. My worst side effect was from the Neulasta shot I was given after each treatment.

      I had a PET scan that showed no evidence of disease after that. I went on Rituxan Maintenance, but only completed 2 rounds as I developed allergic reactions to the Rituxan.

      Now, 2 years later, I have been found to be in relapse and have transformed into DLBCL but that had nothing with the R/B protocol.

      over 2 years ago

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