• Does anyone have information about taking Zometa to prevent bone metastases?

    Asked by lynn1950 on Thursday, September 1, 2011

    Does anyone have information about taking Zometa to prevent bone metastases?

    17 Answers from the Community

    17 answers
    • NewFlower's Avatar
      NewFlower

      Hi Lynn,
      According to my oncologist Latest publications are not showing benefits in prophylactic treatment using Zometa for ER+ estrogen positive patients who have undergone Chemo therapy. Because of these new findings my oncologist and I have decided not to use Zometa for prevention of bone metastases.
      Hugs
      New Flower

      about 6 years ago
    • downtoearth's Avatar
      downtoearth

      the initial study was very positive so docs decided to go forward. A subsequent study was not so promising. I have had 3 prophalactic treatments and will receive a fourth then be done. the initial recomendation was 3 years (6), I guess my onc wants to split the difference. The drug does have side effects, and is expensive. I actually had my third today.

      about 6 years ago
    • lynn1950's Avatar
      lynn1950

      Thanks, NewFlower and downtoearth. It's discouraging that Zometa doesn't appear to be that helpful with bone metastases. : (

      about 6 years ago
    • mspinkladybug's Avatar
      mspinkladybug

      like all drugs what works for some do not work for others. I have 1 friend on it and it is helping and 1 who is did not help so talk to youronc about it take side effect

      almost 6 years ago
    • Merianne41's Avatar
      Merianne41

      I have started taking Femara which is anaromitas inhibitor with Zometa. Zometa is a bone strengthener. I am stage four and so far the combination has cut my cancer numbers in half to a third each time. I believe that is due to the Femara. The bone strengthener iis given because bone cancer, whether it is caused by the blood stream or lymph nodes, starts to break down bones and if the patient has a fall it is worse than a normal person. Also, you can see by what is written here is that people have different experiences with it. It should not be all of the treatment but many people here at the cancer center that I go to have found it helpful. I am stage four and it is working so far. If you are worried, get a second opinion from another oncologist. Your sister and yourself need to be realistic in that you have to give most things a chance and that some drugs help people and some don't. Just make sure that is all that they are doing for her. As I said, studies differ on whether something is helpful are not and results are individual. This is the third time with me for cancer. I had not taken an aromitas inhibitor such as Femara for four years. God bless!

      almost 6 years ago
    • Merianne41's Avatar
      Merianne41

      I forgot one thing. zometa has a website. S

      almost 6 years ago
    • bccage's Avatar
      bccage

      I was on Zometa for 1-1/2 yrs....didn't notice any side effects.. Last month onc switched to X-GEVA

      Said it is suppose to help bones more. I'm stage four breast cancer, now in bones...have no pain yet & feel well

      over 5 years ago
    • Lisa626's Avatar
      Lisa626

      I had a bad reaction to Zometa. Chills, fever, weakness. So my oncologist changed me to Aredia. I completed 2 years of Aredia bone infusions every 6-8 weeks and haven't had any cancer growth or spread!

      over 5 years ago
    • Lori928's Avatar
      Lori928

      I have been on zometa for 1 1/2 years. I had one "tiny" area of my sternum with cancer (breast)...it was radiated along with me being on Femara. I started on monthly infusions, then moved to every 3 months, now I am getting the infusions every 4 months. My scans are showing up NED. From what I understand if there is not any cancer in the bones, the drug is too intense and the side effects may be too intense just to keep the bones strong. In answer to your question lynn1950, I think your oncologist made a good decision not to use it as a prophylactic means. Be well...

      over 5 years ago
    • mykidshavepaws' Avatar
      mykidshavepaws

      Interesting question. I have stage IV lung cancer and had 2 spontaneous rib fractures. That's how my cancer was initially diagnosed because they did a chest X-ray due to the severe pain. The bone scan was negative for metastasis. My oncologist is recommending Zometa even though I expressed reservations (primarily because of side effects). He also said it can help in prevention of bone metastasis. I'm wondering if the bone scan is really accurate. I am getting the Zometa along with chemo but I'll be tested for bone density also to see if the fractures may be related to osteoporosis. I was diagnosed with osteopenia but it's been at least 2 years since my last test. Trying to read all I can between the maze of appointments. I'll be interested to see what you decide.

      over 5 years ago
    • lynn1950's Avatar
      lynn1950

      Thank you, everyone, for your responses.

      over 5 years ago
    • Rosebud's Avatar
      Rosebud

      Hi Lynn,
      My oncologist and I came to the same conclusion as New Flower.
      Rosebud

      about 5 years ago
    • bridget's Avatar
      bridget

      Taking it right this minute. Have had no side effects and my last scan showed very little in the bones! Have it once a month. I think they have me taking it for 12 months total.

      about 5 years ago
    • vizslagirl's Avatar
      vizslagirl

      i've been on Zometa for 18 months b/c my cancer recurred in my bones. my understanding is that it is not necessarily a prophylactic treatment. my oncologist enrolled me in a clinical trial to test whether Zometa can actually lower the tumor cell count in the blood once one IS diagnosed with bone cancer. i think the clinical trial is still ongoing but i had to drop out of the study. HOWEVER, i am still getting a monthly infusion of Zometa to strengthen my weakened bones, and so far i have not noticed any side effects at all. i do not know how much longer i will have to stay on Zometa, i've been told up to 5 years is generally the maximum amount of time. my oncologist can tell me more...
      as far as "preventing" bone metastases, i do not know if there is really any help with that. i think it really depends on the TYPE of cancer or even type of breast cancer you have, and how it works in your body. estrogen/not estrogen may be a bigger part of that. certainly the hormonal aspect of your cancer is something to deeply discuss with your oncologist.
      i hope my info helps you a little bit, and i hope that you don't have to deal with any recurrence! *fingers crossed*
      : )

      about 5 years ago
    • peddienurse's Avatar
      peddienurse

      I did not receive/am not receiving Zometa as part of my breast cancer regime, however my Dad had received Zometa during his treatment for prostate cancer as a "teflon for the bones" as his oncologist called it...it did work for him for quite a while.

      about 5 years ago
    • RNTracyOCN's Avatar
      RNTracyOCN

      Zometa is a biphosphonate. When you see the commercials with Sally Field advertising Boniva, it's essentially the same thing but the iv form is 100 times more potent. There is a standard dose but CMP's are drawn which show you kidney function to dose the drug.

      about 5 years ago
    • dandir2's Avatar
      dandir2

      What is bone metastases? I have not heard of this. As a matter of fact, I am kind of in the dark when it comes to side effects of treatments???

      almost 5 years ago

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