• Estrogen question

    Asked by MarcieB on Sunday, December 5, 2021

    Estrogen question

    Recently I read an article about the latest findings in a quest to understand alzheimer's. One of the points made was the observation that women are more vulnerable to the disease when their estrogen levels drop. (?!) So, here we are, taking anastrozole, and other estrogen blocking drugs to decrease our chances of cancer...but does it, in turn, INCREASE our chance of Alzheimers? It sure doesn't seem like a very good choice! Does anyone have information along those lines?

    19 Answers from the Community

    19 answers
    • ChicagoSandy's Avatar

      I still say that MOs have an obligation to tell their patients why they need to take an aromatase inhibitor, because too many laypeople still have the mistaken impression that ovaries make much (if any) estrogen even after menopause (and that removing ovaries means the end of estrogen production). And all doctors have an obligation to tell people why they are prescribing a certain medicine--the patient shouldn't have to ask nor even think they need to ask.

      I also feel that patients have an obligation to learn all they can about their medical conditions--and that goes double (or even triple) for cancer.

      And the "observation" that was "overly simplistic" was the one made by the *writer of the article* Marcie read, not by Marcie. (Read the original post about the article; "One of the observations made..."). Again, though, I am shocked that her MO did not explain to her why we postmenopausal ER+ bc patients need to take a drug that inhibits aromatase, and that the body still makes enough estrogen to fuel a tumor, even without functioning ovaries. That doctor dropped the ball.

      5 months ago
    • MarcieB's Avatar

      Geez. I'm sorry I asked.

      5 months ago
    • ImWorthIt's Avatar

      Though I cannot speak for Marcie, perhaps the doctor did offer her an explanation and, in the fog of trying to remember a thousand medical things, the explanation was either unclear, given in technical terms, or just missed when she was trying to take in a lot. I do love that I get notes from my doctors after each visit. The notes are always simple/basic, but sometimes they remind me to ask for more information or to clarify something.

      I think many of us think we hear everything, but sometimes we miss something that gets said.
      I also get medication information with every new prescription when I get something from my pharmacy. Sure, it's mostly filled with technical jargon and often gets tossed in the trash but they do give it to me. Last year, my doctor increased my dose of synthroid- a medicine I have been on for most of my life (although in my youth it was not synthetic). I told the pharmacist I didn't need the printout, but they gave it to me anyhow because it is their policy (my pharmacy's) to give the information any time a new medication is given even if it's just an increased or decreased dose of something the patient takes regularly. So I have a few backups.

      In any case, Marcie is certainly not stupid or foolish. I don't think Sandy means to be unkind. I think she tries to impart information, but sometimes makes assumptions that are in no way stated in the prior posts.

      5 months ago

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