• Experiences with Prolia

    Asked by Nanzee on Wednesday, February 15, 2017

    Experiences with Prolia

    My oncologist offered me Prolia along with my anastrozole. I have lowered bone density from my last scan ten years ago, but it's not osteopenia yet. I've been informed of the risks and benefits, and have just about decided to go for it. I'd appreciate hearing from others who have taken this drug and have an opinion, pro or con.

    7 Answers from the Community

    7 answers
    • cak61's Avatar
      cak61

      Are you able to take Tamoxifen?
      I was on it for a year and a half, then switched to Arimidex after a hysterectomy, and saw my bone density decline and diagnosed with osteopenia. After three and a half years, I was not tolerating Arimidex so doctor suggested going back on Tamoxifen, and my last bone density scan showed improvement.
      Tamoxifen actually increases bone mass.
      AI's offer only a very slight improvement in reducing recurrence compared to Tamoxifen.

      10 days ago
    • Jbro's Avatar
      Jbro

      I got prolia injections every 6 months while on anastrozole. My bone density remained good and I didn't have any noticeable side effects. I switched to tamoxifen because of side effects from the anastrozole but couldn't tolerate it either. Now taking Letrozole - onco is watching to see if I need to go back to prolia injections. I hate the AI's,! 1 1/2 years to go...

      In the beginning I had a Zometa infusion which made me pretty sick with flu like symptoms for several days. Prolia was tolerated much better.

      10 days ago
    • sjk's Avatar
      sjk

      I have been taking prolia with anastrozole for 3.5 years. I haven't had any problems with prolia. I've read it can sometimes affect your teeth but I have not experienced that problem.

      10 days ago
    • Joline's Avatar
      Joline

      I have been on Letrozole for 9 months and started the Prolia injections shortly after that. I have had no side effects from the Prolia. I already have osteopenia and my oncologist recommended Prolia since it helps prevent recurrence of breast cancer.

      10 days ago
    • debsweb18's Avatar
      debsweb18

      I was already on fosamax pre breast cancer for osteopenia. I developed reflux so I quit taking it. This was after being on AIs for a couple of years. I've been on them for over 5 years now with almost 5 more to go. I'm still osteopenic, but had my first prolia injection several months ago with no side effects. My doctor said they're finding that prolia helps prevent the cancer from coming back. An added bonus!

      9 days ago
    • Larae55's Avatar
      Larae55

      I have read good things here. People I have talked to and also read about have had such negative bad experiences. My doctor wants me to do prolia. But I'm very scared. Overall the ratings are only a 4.1 improvement. I read every thing I can on the drug

      9 days ago
    • Nanzee's Avatar
      Nanzee

      Interesting news! I hadn't heard that Prolia has anti-cancer benefits. Can't wait to find out more! My oncologist said he has used much larger doses for cancer that has spread to the bones, and has never had a patient get jaw necrosis. My concern was something I've read about, that the balance of osteoclasts and osteoblasts is upset, so that the bone is older and more brittle even though it's denser. I'm getting my first dose soon, along with required education (and I believe a consent form, though I'm not sure about that.) I can't take Tamoxifen; have to take the AI, and I really appreciate the positive answers. Thanks!

      9 days ago

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