• Explain the Differences please

    Asked by little_fut on Friday, February 22, 2013

    Explain the Differences please

    what is the difference between stage and grade? How do they determine stage?

    6 Answers from the Community

    6 answers
    • karen1956's Avatar

      Grade is how slow/fast the cancer is growing....there are three grades....1,2,3.....Stage is related to how "advanced" the cancer is....stages are 0,1,2,3 and 4....4 is generally mastasticized cancer. Within the stages there are letters, A,B and C....but I think that is only within stage 1,2,3. Any stage can have any grade.....They determine stage by tumor size, node involvement and a third thing that escapes me at the moment.....

      over 3 years ago
    • nancyjac's Avatar

      Grade applies to a tumor, stage to a cancer. A cancer can consist of multiple tumors or no tumors at all.

      Tumor grade classifies cancer cells within a tumor in terms of how abnormal they look under a microscope and how quickly the tumor is likely to grow and spread. Many factors are considered when determining tumor grade, including the structure and growth pattern of the cells. The specific factors used to determine tumor grade vary with each type of cancer.The cells of Grade 1 tumors resemble normal cells, and tend to grow and multiply slowly. Grade 1 tumors are generally considered the least aggressive in behavior. Conversely, the cells of Grade 3 or Grade 4 tumors do not look like normal cells of the same type. Grade 3 and 4 tumors tend to grow rapidly and spread faster than tumors with a lower grade.

      Staging describes the severity of a person’s cancer based on the extent of the original (primary) tumor and whether or not cancer has spread in the body. Generally, stage 1 is a single small tumor with no cancer found anywhere outside that tumor. Stage 2 generally means there are multiple local tumors or spread to near my lymph nodes, stage 3 is spread to other surrounding areas or organs such as the skin, and stage 4 indicates metastasis to remote locations through the lymph or vascular systems..

      over 3 years ago
    • BuckeyeShelby's Avatar

      My oncologist explained grade as how mutated the cells are. The more mutated the cells, the more aggressive the cancer. Grade 1 is slightly abnormal, grade 3 is highly mutated. Stage is how far cancer has spread, 1 thru 4. 1 means it's in the inital site. 4 is it's spread further. Some types of cancer differentiate further. Endometrial has a 4A & 4B. I have 4 A, whichmeans it's spread beyond the pelvis, in my case the fat layer over the abdominal organs. B means it's spread to places like the bladder or intestines.

      over 3 years ago
    • JennyMiller's Avatar

      The size of my tumor pushed me from a Stage II to Stage III. My margins were clear but I had lymph node involvement. Even though I was Stage III -- it had not spread to other surrounding areas or organs. With the structure of my cells, they added the word Pleomorphic to my diagnosis. Good Luck!

      over 3 years ago
    • kathykkl's Avatar

      It's a lot of information to take in and just trying to understand it all can be overwhelming. Karen!956's answer is the one that most closely matches my understanding. If you have IDC and are going to have a lumpectemy your surgeon will also biopsy at least one lymph node..that may change your stage and grade..or the recomendation for or against chemo. It's all pretty scary while you're waiting for the final diagnosis. Your docs should be working as a team to come up with a best treatment plan for your particular cancer and health issues. If you aren't comfortable with your docs there is nothing wrong with getting a second opinion. I did that and decided to have my surgery and treatment at another facility. Because I was more comfortable with their team treatment concept. Just had my 2nd round of chemo and my docs are giving me great support to ease side effects. You're on the right track to learn as much as you can....and you have a great big future!

      over 3 years ago
    • SandiD's Avatar

      The answers here are correct. Check out www.breastcancer.org. There is great info here. Good luck to you!

      over 3 years ago

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