• Folfirinox for chemo

    Asked by teachertara on Monday, February 3, 2014

    Folfirinox for chemo

    Anyone on Folfirinox for cholangiocarcinoma and want to share experiences? I am starting it in a week or so.

    6 Answers from the Community

    6 answers
    • jr53's Avatar

      I was on it for pancreatic cancer. I handled it pretty well. I did develop some peripheral neuropathy of my feet and finger tips and my hair thinned. Good luck to you.

      over 6 years ago
    • CrazyHarry's Avatar

      I was on FOLFOX and had the same as jr53 plus some severe reaction to cold as well as swallowing difficulty.

      over 6 years ago
    • teachertara's Avatar

      Thanks, jr53 and CrazyHarry.

      over 6 years ago
    • serenity101's Avatar

      I have done FOLFOX and am now using Irinotecan. On FOLFOX, I had the cold sensitivity, my hair thinned some, and for a while I had first bite pain (on taking the first bite of my food, my jaw would kind of cramp like I had bitten into something extremely sour). I sometimes had mild nausea about 2 days after chemo, but I took Compazine as soon as I started feeling the least bit "off" and I was fine. I also had a somewhat runny nose with blood mixed in and was tired a lot. I'm tired on irinotecan as well, and get bouts of diarrhea which require immodium, and my potassium and magnesium require supplementation sometimes. Most of my hair fell out: I don't think that is very common, but you might want to look at wigs ahead of time just in case (then they can match your current color / style more easily), so you'll have an idea of what you want to get if it happens.

      over 6 years ago
    • moxie's Avatar

      My wife was on gemzar and cisplatin followed by oxaliplatin and folforinox[5FU]. She tolerated both but did have cold sensitivity in her hands as well as increased peripheral neuropathy in her hands and feet. This was not painful...just numbness.../loss of feeling in her hands. Her cancer was extrahepatic and nonresectable. We did do a clinical trial after the chemo did not continue to work. She is now under hospice care. I would urge you to seek out second opinions. Look at clinical trials and targeted therapy. You might the blog of the cancer assassin of interest. She has been living with cholangiocarcinoma for 3 years and is about your age. see www.thecancerassassin.blogspot.com. She is remarkable, determined and strong. Has used naturopathy and nutrition to help her fight. Good luck and God Bless you.

      over 6 years ago
    • Rick1970's Avatar

      Hi Teachertara,
      My wife was diagnosed with stage IV pancreatic cancer in later September, 2013. After 5 rounds of the FOLFIRINOX regimen over that past 3 months, her CT/PET scan on 1/15/14 showed a significant reduction in the cancerous tumor on her pancreas versus a similar scan on 10/18/13. In addition, the 1/15/14 scan showed that the cancerous spots previously shown on her liver are no longer visible. A temporary victory? Frankly, we're not sure, just grateful for any encouraging news.

      While FOLFIRINOX is considered to be a very toxic regimen by some, it's working well for my wife with most of the side-effects mentioned in responses be others. This week, continued her 6th round of treatment with plans to complete rounds 7 & 8 before the next PET/CT scan in Mid-March. Our short-term goal? To confirm that this regimen has stopped or slowed the spread of her cancer. Thus, affording us more quality of life time. Some of which will be used to prepare for what may be next. Best wishes for success in your treatments. Rick

      over 6 years ago

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