Each person is different, I had to take off two days after each treatment, then I went back to work. I wasn't as productive as usual, but I was their, and done about 75% of my job. Others I have talked to have worked right through with no problems.
One of the treatments I had wasn't as bad as the other combo. I don't remember the different drugs I had, but one group of them I had on alternating visits didn't affect me near as bad as the other.
I hope you do well.