• Has anyone else who has had adult medulloblastoma had cancerous cells in CSF fluid?

    Asked by mom24 on Tuesday, January 8, 2013

    Has anyone else who has had adult medulloblastoma had cancerous cells in CSF fluid?

    3 Answers from the Community

    • carm's Avatar

      Mom24, Hello my name is Carm and I am an oncology nurse. I see no one has yet responded to your question here, but I am sure you are looking for answers. Although I am not a patient, I can shed some light on this subject. About 20% of Medulloblastomas occur in adults. They are always located in the cerebellum and because of their proximity to the fourth ventricle, they have a tendency to get into the CSF fluid in that cavity. Even though they do tend to get into the CSF, it is very uncommon for this disease to spread beyond the brain and spinal cord. It is thought to be a mutation on chromosome 17p and a subtype of the TP53 locus, a tumor supressor gene that forgets to turn on and allows the cell to replicate. It is usually treated with chemo like CCNU and Vincristine with sometimes a steroid, or sometimes Cisplatin. Medulloblastomas are considered fast growing, high grade tumors that frequently go to the central nervous system, so what you are describing is not uncommon. You might want to pose this question to a more appropriate support site like the one linked with the ABTA (American Brain Tumor Association). I am sure you will get a much better response to that question there. I hope that I have helped a bit and if you should have anymore questions, please do not hesitate to contact me. It might also be useful for you to go to the website chemotherapyadvisor.com. It is free to join, and here you will find a listing of malignancies and their regimens. It is helpful to know what therapies are available to you. My best to you, Carm.

      almost 4 years ago
    • mom24's Avatar

      Hi Carm,

      Thank you for all of your knowledge and your advice. I will definitely ask the question on the Brain Tumor Website. I do have a few of those bookmarked as well, but haven't explored them all just yet. My son unfortunately had some cells in his CSF. So far, of the three or so people I have talked to with medulloblastoma, have not had the cells in the CSF. He has had one course so far of chemo and will start the second course on Jan. 28th. Thank you again, for taking the time to answer my question.

      Take Care ~

      almost 4 years ago
    • MTraudt's Avatar

      My wife was diagnosed with medulloblastoma in late October 2012. A spinal tap revealed a small amount of cancerous cells in the CSF.

      over 3 years ago

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