• has anyone had a bad reaction to Rituxan?

    Asked by jomar on Sunday, October 5, 2014

    has anyone had a bad reaction to Rituxan?

    I had my second round of Rituxan on Wednesday. On Friday I began having terrible aches in my legs and mouth (teeth and gums). I called the doctor. They said (surprise) take two Tylenol. On Saturday night my legs, neck and back were very painful. I decided to take a bath. When I got out of the tub I noticed my chest was red. I thought it was from the hot water. During the night the aches in my legs worsened, my torso, face and scalp were covered in a rash.My throat started to close and tongue felt numb. Went to the Er on the advice of a nurse at the oncologist's office. They gave me steroids and Zyrtec. My BP was 192/75. It's never been that high in my life. They called the oncologist who prescribed more steroids - Medrol 4 mg. to take for 7 days. I am worried that all these steroids are too much for my body. Just read about the side effects from that drug. I'm wondering if I should take it at all. My question is has anyone had this kind of reaction to Rituxan.Was it discontinued?

    7 Answers from the Community

    7 answers
    • DJS's Avatar

      I think a reaction to Rituxan is fairly commonplace. Everyone I know who gets it -- and it's given to my friends for a variety of treatments, including MS -- gets an infusion of an antihistamine (or something like that -- I forget exactly what it was) to avoid an allergic reaction. If your doctor didn't prescribe this I would definitely ask for it (and maybe even ask why it wasn't included in your treatment to begin with, since it's pretty standard). You should be getting anything and everything to make this road an easier one to travel. Good luck!

      almost 4 years ago
    • Schlegel's Avatar

      DJS is right. I always get Benadryl with my treatment.

      almost 4 years ago
    • andreamk's Avatar

      Hey there- I'm so sorry to hear about all of your troubles! I also had some adverse reactions to my rounds of R-CHOP (which includes Rituxan), including terrible mouth sores/gum pain, and I was told that is pretty normal. My doc gave me a prescription for "magic mouthwash," which basically just numbs your mouth, and it was pretty helpful. During my first round of chemo, I broke out in hives and got an itchy throat from the Rituxan so the nurse pumped me full of benadryl. From then on out I got a dose of benadryl at the beginning of each infusion- never got hives or the itchy throat again. Like DJS mentioned, I would definitely ask for something like this, there's no need to put yourself through anything more than you're already dealing with! Good luck :)

      almost 4 years ago

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