• Has anyone had experience with Methotrexate treatment for Non Hodgekins?

    Asked by glomoy on Tuesday, January 10, 2012

    Has anyone had experience with Methotrexate treatment for Non Hodgekins?

    I have Ocular NHL, and they are concerned that it will invade the Central Nervous system.

    8 Answers from the Community

    8 answers
    • glomoy's Avatar
      glomoy

      Thanks. I have ocular NHL which in some cases at time of originally diagnosed has it in the CNS - 93% do, i am part of the 7% who did not. There was talk initially about the use of Methtotrexate, but because my vision was going they opted to do radiation first. My first brain MRI yesterday was normal (treatment ended 11/17/2011), but the probability of this spreading to my CNS is in my mind, and just wondering what MTX made you feel and the side effects....i have my next brain MRI in April.

      almost 9 years ago
    • Alya219's Avatar
      Alya219

      Methotrexate actually wasn't that bad. I had Pretty much no side effects from it aside from some minor nausea. I have heard of some people that had some more prominante side effects but it's becuse methotrexate can have high toxicity so they monitor you closely and really hydrate you. They also give a drug called lucovorin which my onc referred to it as the antidote for methotrexate. It sounds worse than it is, like I said aside from the minor nausea I felt fine. You don't loose your hair or have really any of the other side effects that most other chemo drugs cause. All in all it was easiest thing about my treatment. Hope that helped, if you want to know anything else please let me know!! :-) made me feel better that I had it cause I wanted a lower risk of CNS relapse.

      almost 9 years ago
    • glomoy's Avatar
      glomoy

      Thanks Alya219.

      almost 9 years ago

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