I took those two drugs together briefly. I was to do 4 rounds as follows: An infusion of oxilaplatin and 2 weeks of daily xeloda, then a week off both drugs. I completed one round but then my doctor discontinued the xeloda because I just could not tolerate the drug. After discontinuing the xeloda I completed the oxilaplatin as scheduled.
Xeloda made me horribly sick. When my surgeon saw me for a follow-up visit after the first round of xeloda, he told me I had lost too much weight (I was losing almost 2 lbs. per day) and recommemded to the medical oncologist that we stop chemo altogether. We compromised by stopping the xeloda and continuing with the infusions.