• Hormonal therapy drugs

    Asked by lola08 on Sunday, April 28, 2013

    Hormonal therapy drugs

    Anyone receiving a combination of Arimedex & Fasoldex injections? Any side effects?

    1 Answer from the Community

    • carm's Avatar

      Hello, I am an oncology nurse and I Am attaching a link to chemocare which is a great site that is free to join and it will tell you about both drugs. The site also has a tab on managing side effects. Let me give you a little info on the rationale of using this combination. Faslodex is a downregulator estrogen receptor drug. It attaches to your estrogen receptors to block estrogen from doing so. When estrogen is blocked, the body will try and find something equivalent to estrogen. What it looks for is aromitase. Arimidex is an aromitase inhibitor. Aromitase is an enzyme that circulates within muscle and skin of the body. It has the capability to change androgen, a hormone made in the adrenal gland, into estrogen. So the arimidex attaches to the aromitase receptors so that it cannot bind to the androgen. Your treatment is kind of a one-two punch that covets any possibility of estrogen production. I hope that the site will prove useful to you until someone who is on the same treatment responds. Good luck to you, Carm RN.


      over 4 years ago

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