With chemotherapy, for my dad, side effects began on or about day three, and started to improve a couple weeks after chemo. His hair returned fully after about three months following the end of chemotherapy. This time around, it's a different drug. So, his hair didn't fall out. Different drugs may produce different side effects for different people. For example, he experienced very little nausea. He has not been through radiation.
Here are a couple booklets on radiation and chemotherapy from the National Cancer Institute (U.S.)
In some instances, I have read, that side effects may worsen. One of those side effects can be peripheral neuropathy-- or that pins and needles feeling you can feel in your feet and hands. However, that has not been dad's experience. With his first cancer, all chemo side effects improved with time.