• How long do side effects of Letrozole (Femara)last?

    Asked by DorothyV on Sunday, December 2, 2012

    How long do side effects of Letrozole (Femara)last?

    I just started Letrozole and will be on it for five years. I have joint pain and hot flashes. Will these side effects last for the next five years, or do they gradually disappear?

    15 Answers from the Community

    15 answers
    • karen1956's Avatar
      karen1956

      It depends....for some people they go way within a few months...others either get used to them or they go away...and some have no side effects.....Gabapentin is good for joint pain and night sweats (so might help with hot flashes).....I endured AI's for 3 1/2 years...but I'm one of those that if there is a side effect, I get it!!!!

      almost 8 years ago
    • JudyS's Avatar
      JudyS

      Karen 1956 is correct - everyone is different and also manages pain differently. I have osteoarthritis prior to diagnosis and any treatment. I was on Femara for about 2 to 3 months and the joint pain was so bad that I could barely walk. I was then put onto Tamoxifen after a 6 week break, but after about 3 to 4 months the pain was back and crippling. I was already on gabapentin for neuropathy and it didn't help with the bone pain or my hot flashes. I had 1 tumor that was treated by lumpectomy, chemo and radiation and a very small tumor that the doctor was giving me the Femara/Tamoxifen for - we both decided that my quality of life was more important and I came off of it. I would suggest talking to your doctor about the pain/hot flashes and see what they recommend. Although gabapentin did not help me with those symptoms, it might help you. Best Wishes!

      almost 8 years ago
    • SandiD's Avatar
      SandiD

      I was on Arimidex for 6 months & the joint pain was terrible! Then I switched to Aromasin for a year. It was a little better, but not a lot so I just started Femara the other day. It is too soon to tell about joint pain or hot flashes yet, but I am so nauseous! I will try to stick it out & see if it goes away. My oncologist said I could go back to whichever one had the least side effects. We sure go through a lot! I wish you the best. I have 5 years on an AI too.

      almost 8 years ago
    • Ann's Avatar
      Ann

      You should also have once a year infusions of RECLAST, which help. I had 5 years of Letrozole and Reclast and survived fine. However, I think your oncologist should know about your reactions, in case s/he can help.
      Ann

      almost 8 years ago
    • Ann's Avatar
      Ann

      This is Ann a second time---I see that I am listed under "colon or colorectal cancer". Just to be sure you know that what I'm writing to you here is relevant, I'm also a BREAST cancer survivor (BOTH sides separately). Ann

      almost 8 years ago
    • BirdieSue's Avatar
      BirdieSue

      I AM 66 YRS OLD HAD BREAST CANCER 15 YRS AGO. I TOOK TAMOXFEN FOR 2-1/2 YRS AND FEMERA FOR 2-1/2 YRS. ALSO 4 ROUNDS OF CHEMO. THE SIDE EFFECTS WERE AWFUL. MY FEET AND HANDS HURT FOR 5YRS. TODAY MY FEET AND HANDS STILL ACHE ALOT, STILL HAVING HOT FLASHES AND REALLY JUST DON'T FEEL GOOD AT ALL. CAN I STILL HAVE SIDE EFFECTS AFTER THIS LONG. THANKS SUSAN.

      over 2 years ago
    • vibhavari's Avatar
      vibhavari

      I started getting muscle and lointpains four months after starting letroze
      However now after 10th month,it has worsened.Walking has become painful.I am jyst learning to accept ir.

      over 1 year ago
    • Eliz's Avatar
      Eliz

      I finished taking 5 years of first Tamoxifen then Letrozole, 2.5 years each. I had bad joint pain in my knees for the full time and hot flashes as well as some foggy mental functioning. I completed the full five years as prescribed. Now 2 months later, without letrozole I am feeling much better. Less pain in the knees but still getting better gradually. There is hope after this med!

      over 1 year ago
    • Medina's Avatar
      Medina

      I take letrozole been taking it 5 years. I never feel good also I have gained weight. I try to dieting exercising and I just can’t loose. Is it the Letrozole?

      over 1 year ago
    • Jackieskinner's Avatar
      Jackieskinner

      Can letrozole cause your hair to thicken ?

      over 1 year ago
    • Jackieskinner's Avatar
      Jackieskinner

      Can letrozole cause hair thickening

      over 1 year ago
    • Blonty's Avatar
      Blonty

      Hi, I have just started taking Letrozole and I feel slightly nauseous in the morning. it wore off after a few hours but I woke this morning very dizzy. Is this something that will wear off as my body gets used to the drug?

      over 1 year ago
    • Josiesdaughter's Avatar
      Josiesdaughter

      Blonty. I am new to this also. After 4 weeks the dizziness is so bad I can't function. I also feel like my vision has changed too. My thinking is not good either. I stopped the Letrozole and called my Dr. I have an appt in two weeks

      over 1 year ago
    • macfightsback's Avatar
      macfightsback

      I am not familiar with your chemotherapy agent. I do know that how long side effects last is very individual and which side effects you suffer from are individual. I still have neuropathy in my left foot and ringing in my ears. Both are from previous chemo I received. I would consult your physician about any long lasting side effects. Also Palliative Care could be helpful. Palliative Care is for the management of symptoms and is not just for people at the end of their life. They helped me resolve a problem in 2015.

      over 1 year ago
    • Survivr1's Avatar
      Survivr1

      To blonty, I've taken letroze for 2 yrs. Side effects not too. Bad.what if you take it at night, I do after dinner. I also take glucosamine with chondroitin:-\
      We

      over 1 year ago

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