• How long do side effects of Letrozole (Femara)last?

    Asked by DorothyV on Sunday, December 2, 2012

    How long do side effects of Letrozole (Femara)last?

    I just started Letrozole and will be on it for five years. I have joint pain and hot flashes. Will these side effects last for the next five years, or do they gradually disappear?

    5 Answers from the Community

    5 answers
    • karen1956's Avatar
      karen1956

      It depends....for some people they go way within a few months...others either get used to them or they go away...and some have no side effects.....Gabapentin is good for joint pain and night sweats (so might help with hot flashes).....I endured AI's for 3 1/2 years...but I'm one of those that if there is a side effect, I get it!!!!

      over 4 years ago
    • JudyS's Avatar
      JudyS

      Karen 1956 is correct - everyone is different and also manages pain differently. I have osteoarthritis prior to diagnosis and any treatment. I was on Femara for about 2 to 3 months and the joint pain was so bad that I could barely walk. I was then put onto Tamoxifen after a 6 week break, but after about 3 to 4 months the pain was back and crippling. I was already on gabapentin for neuropathy and it didn't help with the bone pain or my hot flashes. I had 1 tumor that was treated by lumpectomy, chemo and radiation and a very small tumor that the doctor was giving me the Femara/Tamoxifen for - we both decided that my quality of life was more important and I came off of it. I would suggest talking to your doctor about the pain/hot flashes and see what they recommend. Although gabapentin did not help me with those symptoms, it might help you. Best Wishes!

      over 4 years ago
    • SandiD's Avatar
      SandiD

      I was on Arimidex for 6 months & the joint pain was terrible! Then I switched to Aromasin for a year. It was a little better, but not a lot so I just started Femara the other day. It is too soon to tell about joint pain or hot flashes yet, but I am so nauseous! I will try to stick it out & see if it goes away. My oncologist said I could go back to whichever one had the least side effects. We sure go through a lot! I wish you the best. I have 5 years on an AI too.

      over 4 years ago
    • Ann's Avatar
      Ann

      You should also have once a year infusions of RECLAST, which help. I had 5 years of Letrozole and Reclast and survived fine. However, I think your oncologist should know about your reactions, in case s/he can help.
      Ann

      over 4 years ago
    • Ann's Avatar
      Ann

      This is Ann a second time---I see that I am listed under "colon or colorectal cancer". Just to be sure you know that what I'm writing to you here is relevant, I'm also a BREAST cancer survivor (BOTH sides separately). Ann

      over 4 years ago

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