• How quickly does Gabapentin help with pain from CIPN?

    Asked by Vivenia on Thursday, June 6, 2013

    How quickly does Gabapentin help with pain from CIPN?

    During my 6 months of chemo I thought that I had gotten lucky with my peripheral neuropathy, the pain and numbness were limited to only my fingertips and toes, and the pain was sufficiently managed by Amytriptylene. After chemo ended the numbness and pain have worsened quite a bit. I have been in so much pain that I can't sleep at night, or function during the day. I am on my 8th day of Gabapentin and have not noticed any change in my level of pain. Is there a period of time that the drug needs to work through my system before it will become effective?

    8 Answers from the Community

    8 answers
    • BuckeyeShelby's Avatar

      I've been on Gabapentine for awhile. I didn't think it was doing anything. Until I ran out over a weekend and couldn't get to the pharmacy. Oh, yes, it really was doing something. The pain and numbness was significantly worse w/out the meds. But I really truly didn't know it was doing anything until that time. Good luck.

      about 5 years ago
    • ticklingcancer's Avatar
      ticklingcancer (Best Answer!)

      The thing about gabapentin is that you have to play with it to find the dose that works. I started with 100 mg and didn't notice any difference in the pain. I then moved up to 300 mg. Still nothing. I now take 900 mg every morning and I have ZERO pain. You can take up to 3600 mg of gabapentin so as I said, it's just a matter of finding the dose that works. Hope this helps. Good Luck

      about 5 years ago
    • Ydnar2xer's Avatar

      I have also been bothered by neuropathy--I nearly always have it in my toes and on the bottoms of my feet. I've tried gabapentine with very little success--I've tried dosages from 100 mg to 1200 mg. I finished chemo in January, but STILL am bothered with neuropathy every day! I work out 5x a week, and it's tough on the elliptical when your feet are numb~it's tough ANYWAY! So if you find something that works, please let us know!

      about 5 years ago
    • myb's Avatar

      During chemo, I was on 600mg of Alpha Lipoic Acid for hand and foot cramping which I stayed on when the tingling and numbness started after chemo. I tried adding 300mg of Gabapentin at bedtime which helped to get me to sleep with the CIPN but had me dragging all day. I then tried 100mg which didn't help getting me to sleep. At the same time, I started the Livestrong program at my local YMCA which had me so tired, I slept well on those nights. I am almost 9 months out from chemo and have just learned to live with it.

      about 5 years ago
    • fightingintx's Avatar

      I have been off Chemo 7 months now. I have some discomfort in my hands and a lot in my feet. My feet are numb and so is a small portion of my calf. I take 600 mg X 3 a day of Gabapentine and I still have a problem. I have just adjusted to it. The only time I have a problem is driving. Guess I have been doing this for so long that I pretty much know where to put my foot. Thank goodness its automatic!

      about 5 years ago
    • ElizaM's Avatar

      Gabapentin has certainly worked for me. I still have some numbness in my feet, worse in one than the other, but I am functional. I don't recall that it took more than a couple of days to work. I wonder if you are taking them 3 times a day. I'm able to get by with only 2 a day and suspect if I took the 3 a day I wouldn't have any neuropathy at all. Maybe discussing it with the pharmacist would help. They are far more knowledgeable than doctors about the effectiveness of medications and how they interact with one another. Good luck - it's miserable and just goes to show that chemo just keeps on giving! :(

      about 5 years ago
    • Vivenia's Avatar

      Thanks everyone! I talked to my doctor and he upped my doseage. He said that this may take 2 weeks to reach peak efficiency - and to call him if I was still having trouble and we'd adjust doseage again. So far I am experiencing more relief, there is still pain but the intensity has decreased enough that I was able to get good sleep last night for the first time in weeks.

      about 5 years ago
    • KarenN@StF's Avatar

      For anyone suffering from CIPN out there- there is evidence to support the use of therapeutic massage specifically for CIPN. This can be coupled with Gabapentin. I would seek a massage therapist trained to work with cancer patients and one who has been trained in this type of massage. Good Luck!

      about 5 years ago

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