• I saw this article from the National Cancer Institute that these drugs have been approved, I think it's new, but have anyone used them?

    Asked by StegalMan on Thursday, August 9, 2018

    I saw this article from the National Cancer Institute that these drugs have been approved, I think it's new, but have anyone used them?

    On July 10, the Food and Drug Administration (FDA) approved the combination of two immunotherapy drugs—ipilimumab (Yervoy) and nivolumab (Opdivo)—for the treatment of some patients with metastatic colorectal cancer who have been treated previously with standard chemotherapy drugs.

    https://www.cancer.gov/news-events/cancer-currents-blog/2018/fda-ipilimumab-nivolumab-colorectal-dna-repair

    6 Answers from the Community

    6 answers
    • geekling's Avatar
      geekling

      This was a Phase 1 study. Keytruda did almost as well on its own (6% differential) and the combo has more side effects.

      I havent done this. I imagine no one here has because there were only 82 people in the study. They will likely be looking for another study. Get in touch with either or both Bristal Meyers which funded the study or Dr. Gulley of the

      https://ccr.cancer.gov

      To find out when or if there will be a second study and if you can volunteer if you wish. Have you tried Keytruda on its own yet?

      Best wishes.

      2 months ago
    • LiveWithCancer's Avatar
      LiveWithCancer

      Yervoy and Opdivo gave both been around for awhile. It is probably just now being tested for colon cancer (either separately or in combo).

      (Sorry ... rushing down to a meeting. I didn't get to read the article which may be painfully obvious. )

      2 months ago
    • JaneA's Avatar
      JaneA

      LiveWithCancer is right. They have been around for a while. Now they are approved for metastatic colorectal cancer.

      Here's an article that we just had about these drugs - they are immunotherapy.
      https://www.whatnext.com/blog/posts/immunotherapy-the-future-is-almost-here

      2 months ago
    • geekling's Avatar
      geekling

      Here is another possibility and its phase 1 trial. This drug leaves healthy cells alone and only destroys cancerous cells.

      https://amp.cincinnati.com/amp/948394002

      2 months ago
    • biga17133's Avatar
      biga17133

      Wow that is very promising @geekling if this works it could mean so much, praying it works and wanting it to badly !!! thanks for letting me read this I would have never heard of it unless you shared this!

      2 months ago
    • Skyemberr's Avatar
      Skyemberr

      I haven't tried them because I have the wrong mutation, but the doctor added avastin, stivarga and lonsurf to my list of drugs I could have. I am a KRAS mutatant.

      2 months ago

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