• I've looked up all of the descripters that my doctor mentioned and have a decent understanding of all but one. What does K16 refer to?

    Asked by awesomegramma on Thursday, September 27, 2012

    I've looked up all of the descripters that my doctor mentioned and have a decent understanding of all but one. What does K16 refer to?

    2 Answers from the Community

    • nancyjac's Avatar
      nancyjac

      Keratin is a protein expressed through the KRT16 gene. It's presence in cancer cells indicates an over expression of the protein or mutation of the gene which aids in the growth and cell division of the cancerous cells, similar to cancers that are HER2, ER, or PR positive.

      over 4 years ago
    • Elle's Avatar
      Elle

      The Ki-67 test shows the proliferation rate, or how quickly or slowly the cancer is likely to grow. The number assigned to your tumor, 1 to 100, is how many cells were dividing or preparing to divide at the time of your biopsy. For example, the number assigned to mine was 60, meaning 60 out of 100 cells were dividing when my biopsy sample was taken. The higher the number, the more aggressive the cancer, and on the flip side, the lower the number, the slower growing the cancer. It's very important to know to help guide your treatment.

      What was your Ki-67 number? Be sure to talk with your doctor about everything on your pathology report. He/she shouldn't have any hesitation in explaining anything and everything you ask about it.

      over 4 years ago

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