• Is amyloidosis a common complication with multiple myeloma?

    Asked by MyelomaBeacon on Monday, March 25, 2013

    Is amyloidosis a common complication with multiple myeloma?

    1 Answer from the Community

    • carm's Avatar

      Hello, I am an oncology nurse and I might be able to help answer your question. An Amyloid is a deposit of proteins in vital organs or tissues. With multiple Myeloma, this is a disease with genetic mutations that result in uncontrolled tumor growth or proliferation. Multiple Myeloma patients produce excess proteins called immunoglobulin. When these immunoglobulin proteins clump together (an Amyloid), they tend to deposit in tissue or organs and can then lead to organ dysfunction. This can happen whether the patients' disease is active or in remission, so amyloidosis can occur even in the absence of the cancer cells. It is a common hallmark of the disease. I hope this helps explain it. Best of luck to you, Carm RN.

      over 5 years ago

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