Mandi - I'm not single, but I might as well be. Also my sisters have taken me to a couple of appointments but not very many in the grand scheme of things. I have had to rely on a small group of friends and my mother in law for all of my support with rides and also helping with meals.
For help with appointments/rides/meals/household chores, definitely let any friends, neighbors, etc. know that you could use some help. Also, reach out to the American Cancer Society. They have volunteers as well as access to a database of other organizations that can help you.
For emotional support, your clinic should have a social working or be able to recommend a support group. For me, I have mostly relied on my internal strength and determination to get through this.
Be strong. Be courageous. Accept help. Ask for what you need or it will eat you up inside. People don't realize how hard of a struggle all of this is unless they have lived through it.