• Is anyone familari with the Rituxin and bendamustine regimen?

    Asked by CourtW on Tuesday, October 16, 2012

    Is anyone familari with the Rituxin and bendamustine regimen?

    I have had 6 treatments of RCVP and the cancer has not grown but it has not diminished either. So, I am starting all over again this week with rituxin and bendamustine and I am hoping someone can tell me about their experience with it.

    8 Answers from the Community

    8 answers
    • GregP_WN's Avatar
      GregP_WN

      Hi CourtW, someone will probably come along soon and answer, but in the mean time if you want to search, go to the people tab, then on the left side of the page you can search for people with your diagnoses. You will be able to see their experiences, and one of them may have that regimine listed. If so you can send them a msg and chat about it.

      Let us know if you need any help. We hope your next round of treatments are smooth and quick.

      greg P
      3X Survivor
      Team whatNext
      Community Mgr

      over 4 years ago
    • carm's Avatar
      carm

      Hello, I am an oncology nurse and let me direct you to a wonderful website called the Chemotherapy Advisor at chemotherapyadvisor.com and on the right side of the home page about half way down you will see cancers and their regimens. Here you will find the information of the chemo you seek. This site is free to join. If you still have questions, sometimes it is best to ask your oncologist for the names and phone numbers of two of his patients who have or have had the same treatment so that they can tell you their experiences with the regimen. A good oncologist is proud of their work and are usually willing to connect you to someone he has treated in the same manner. Best of luck to you, Carm.

      over 4 years ago
    • CourtW's Avatar
      CourtW

      Thank you - I will take a look at this website.

      over 4 years ago
    • Harry's Avatar
      Harry

      I had that combination of drugs. Bendamustine is very easy to take. You should not experience any major side effects.

      Rituxan is also considered a comparatively easy drug to take. Most people have a comparatively minor reaction the first time (hives are common) but they should go away quickly. After that the reactions should be less than the first time. Some people do experience more severe reactions, but they should be treatable with steroids, etc., and by slowing down the rate of injection. And then there is me. :-) My oncologist--very expereinced--has never come across a reaction such as mine before or since. I can't take Rituxan again.

      All in all, this should be relatively easy. No hair loss (unless you are losing it anyway :-) ) and mild reactions over in a day or so. Tell your oncologist and the nurses if you have anything more severe. I'd do it again if I didn't have the severe reaction. There's a drug in clinical trials, Ofatumumab, that eliminates the allergen in Rituxan, but that won't be available for a while. For now, you will probably have a good experience with Rituxan.

      Bendamustine has a fascinating history. Back in the '70s the East German government ordered their doctors to come up with a cancer drug as good as one the US wouldn't export to them. They came up with a better. After the Berlin Wall fell, first West German, then Western European, and now US doctors were introduced to Bendamustine. The biggest problem is that no one has ever done long term follow up studies. The East Germans didn't care and no one else has had the time or the research budget. Like a lot of cancer drugs, this might cure you now, but 30 years down the road who knows? Still, a drug that buys you 30 years without a lot of chemo side effects can't be all bad. We are the long term study. :-)

      over 4 years ago
    • marmot's Avatar
      marmot

      I can give you a little info. My husband has follicular lymphoma and is being treated with the R&B chemo regimen. He has only had one round, but already the cancer is receding. He will have 6 treatments, 1 month a part. Karmanos Cancer Institute in Detroit, where he is going, says they are having the best results with this combo. So good luck to you. I think this time it will work :) Sue

      over 4 years ago
    • Msrobin315's Avatar
      Msrobin315

      I had very good results this past 7 months...I had 6 rounds of R & B and now Im in remission and on a every 2-3 month maintenance of Rituxan..I was diagnosed 3/5/12 and started treatment in June '12. Have to have a f/u PET scan soon.

      about 4 years ago
    • marmot's Avatar
      marmot

      My husband has follicular lymphoma, and he is having his 5 treatment of the Rituxin/bendamustine regimen. Cancer is almost gone. He has a treatment this week and then one more the end of Feb. He is being treated at Karmanos iin Detroit, and they insist this is the best way to go. Good luck!

      about 4 years ago
    • CourtW's Avatar
      CourtW

      UPDATE - I have had 4 treamtments with the Rituxin Bebamustine combo and it has taken me longer to recover than when I was doing the RCVP combo. I am going in for a PET/CT scan in a couple of weeks and am PRAYING that I will be done and can start the maintenance regimen. If the cancer is still there - I will have to have 2 more treatments. Thanks everyone for your comments!

      about 4 years ago

    Help the community by answering this question:

    Create an account to post your answer Already have an account? Sign in!

    By using WhatNext, you agree to our User Agreement, and Privacy Policy


    Read and answer more b-cell lymphoma questions.  Also, don't forget to check out our B-Cell Lymphoma page.