• Is there a link between ovarian and thyroid cancer?

    Asked by avonlea02 on Friday, February 22, 2013

    Is there a link between ovarian and thyroid cancer?

    I was diagnosed with Stage IIIc ovarian cancer last February. After extensive surgery and chemo, I went into remission. On my PET scan to confirm that, thyroid nodules were discovered. Biopsies revealed thyroid cancer just a few days ago, and I will need a thyroidectomy. I am told this is another primary. But my question is whether there is any link between the two? I was also tested and found to be BRCA positive. I am wondering if this is contributory? I am positive and hopeful. But trying to understand as much as I can about this. I plan to beat this monster!

    7 Answers from the Community

    7 answers
    • GregP_WN's Avatar

      Sorry for the "redo" on another diagnosis. That's no fun, I've been where you are twice when told I had it again. Once it was a recurrence, the second time it was a different primary. I just told myself it was no big deal, just another "inconvenience" for my daily life. I vowed I wouldn't let it change my daily schedule any more than absolutely had to. And I reassured myself by saying that I have done it twice before, I'll just do it again.

      As far as your two being related, I cannot say. Doesn't seem like they would be. I asked the same question when I was dx'd the third time. I was convinced It had to be from the previous two. Who knows? I would bet the docs don't, at least they said they couldn't connect them.

      Here is a link to both types of cancer on our diagnoses page, maybe you can get some info there.

      Someone else should have some info for you soon.

      over 3 years ago
    • SueRae1's Avatar

      Hugs - I too have two active cancers - Kidney and Breast. I am seeing a geneticist who specializes in cancers and have several different types of gene panels done. You might want to ask your oncologist about a referral.

      over 3 years ago
    • nancyjac's Avatar

      There is scientific evidence to support a connection, but it is in the other direction. Hyperthyroidism, Cowden's Disease, and BRCA mutations increase the risks of ovarian cancer, but I am not aware of any increased risk for thyroid cancer from having had ovarian cancer or being BRCA positive.

      over 3 years ago
    • carm's Avatar

      4avonlea02, there is a genetic link between them in that both can be triggered by mutations in a tumor suppressor gene. One gene is the p53 and the other is the HOX gene. I have attached a link regarding the HOX gene. Best of luck, Carm RN.


      over 3 years ago
    • Carol-Charlie's Avatar

      Well pooh... I didn't know that Carm.... I had Stage IV Ovarian cancer- it was upgraded to IIIC after surgery... AND I'd been on tyroid meds for over 30 years by then. No cancer, just took pills to turn it off as without pills It grew and grew... Now I know.

      over 3 years ago
    • Blepta's Avatar

      Hi, sorry to hear about all you are going through. I also have the BRCA mutation. I have been told that it results in an increased risk for breast and ovarian cancers primarily, but also a smaller increased risk for pancreatic and peritoneal cancers. The research is ongoing, with melanoma and other cancers being studied for links to the mutation. I found that FORCE http://www.facingourrisk.org/ was an extremely helpful source of information about hereditary cancer risk.

      over 3 years ago
    • Blepta's Avatar

      My aunt who has the BRCA mutation has had tongue, ovarian, and pancreatic cancer. She just celebrated her one year anniversary since the most recent diagnosis. One of her doctors commented that people with multiple diagnoses of different cancers have a better survival rate than those who have recurrence of the same cancer, so that shoud be good news for you!

      over 3 years ago

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