• Local recurrence after unilateral mastectomy. Chemo or not?

    Asked by Lilly on Thursday, November 28, 2013

    Local recurrence after unilateral mastectomy. Chemo or not?

    I had a 2.5 cm grade 2 tumor with no lymph nodes involved 2 years ago. Had unilateral mastectomy at that time and followed by tamoxifen. Oncotype DX test score 24 (~16%). No chemo or radiation done at that time.

    Now cancer has recurred locally. Not sure yet if lymph nodes are involved this time. Radiation will be performed. Medical oncologist still thinks that I won't benefit from chemo. Instead, he suggests shutting down my ovaries and starting exermestane (an AI agent) for 5 years. My concern is that without chemo, there will be a higher chance that there are living cancer cells in my body after surgery, then after 5 years when I stop exermestane, these cancer cells can grow fast again. Is my understanding correct? Should I insist on chemo this time?

    3 Answers from the Community

    • HearMeRoar's Avatar

      I am no expert, but if I were you I'd get a second opinion!! I had my diagnosis earlier this year... 1.5cm tumor and 3 nodes involved and got the whole ball of wax - mastectomy, chemo, rads and 10 years tamoxifen... sorry you have to go thru it again!

      almost 6 years ago
    • ld_105's Avatar

      I would get a second opinion. Ask for statistics and maybe change hospitals.

      almost 6 years ago
    • baridirects' Avatar

      I have to agree about getting a second opinion. You have already had a local recurrance; at this point, I'd tend to want to be as aggressive as possible this time around to do everything you can to get it wiped out permanently. Of course, no one has a crystal ball as to the future, but if you take an aggressive posture, and you do end up with further issues later on, at least you won't be having to cope with the "Would it have been different if I had done...." question in your heart.

      Sending you lots of healing energy!


      almost 6 years ago

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