• Looking for others undergoing immunotherapy following initial chemoradiation

    Asked by Shortstuff on Thursday, March 21, 2019

    Looking for others undergoing immunotherapy following initial chemoradiation

    11 Answers from the Community

    11 answers
    • LiveWithCancer's Avatar
      LiveWithCancer

      Hi Shortstuff,

      I did chemo. Then I went into a clinical trial for immunotherapy. After 4 years, I had to have a bit of radiation. And then I went back on immunotherapy for the last 1.5 years or so. Will that work?

      3 months ago
    • Dianem's Avatar
      Dianem

      Had chemo first, then 3 years of immunotherapy. Then lung surgery . Then back on immunotherapyforan additional 2 years. .currently there maybe some change so radiation is a possibility. More to come. Overall have done well with immunotherapy.

      3 months ago
    • Shortstuff's Avatar
      Shortstuff

      Wow-currently I am scheduled for 26 biweekly infusions over 52 weeks. Another woman at my oncology center is just finishing her one year. There has been no suggestion of continuing treatment for as long as either of you. I wonder which path is more common? Was you immunotherapy continued because you had remained progression free for that long?

      3 months ago
    • LiveWithCancer's Avatar
      LiveWithCancer

      Hi Shortstuff,

      I think my doctor intends to keep me on Opdivo until it quits working or I develop side effects that can't be ignored. I started out in a clinical trial for it in July 2013. I had infusions every two weeks for 4 years and everything remained stable until one tumor in my lymph node started growing. I had to quit the trial, had radiation to it and went back on Opdivo (but not the trial) a month or so later and have been on it ever since. The radiation took care of the tumor in my neck and the tumors in my lungs have been stable since I started immunotherapy.

      My doctor is a researcher. I think he is treating me for my cancer, but I also think he is interested to see the impact of long-term treatments. (These are thoughts, not what I know for sure. I DO know that he has extra blood drawn from time to time to take a look ... trying to figure out why I have responded so well and for so long ...)

      I have heard other people say that their oncologists say that 2 years is the normal amount of time to get immunotherapy treatments...

      I currently get my treatments, a double dose, once a month. A study was recently published showing it works just as well as biweekly and I like not having to go to the clinic so often. http://www.ascopost.com/News/59802

      Good luck!!!

      3 months ago
    • Dianem's Avatar
      Dianem

      My reponse mimics my friend above . I now go once a month.
      I suspect I will continue until it stops working, which is why I’m anxious about my upcoming pet scan. But I know my oncologist will guide me in the right direction. By the way I did forget to mention neuropathy and arthritis as possible side effects.

      3 months ago
    • 2943's Avatar
      2943

      I am on Imfinzi following chemoradiotherapy . The ‘plan’ is to have it every two weeks for a year. I believe this is following the Pacific Trial protocol. Side effects..a few days of headaches, itching, fatigue. I now take daily Claritin and have a steroid for scalp. All tolerable. 12 treatments down and 14 to go. Hugs!

      3 months ago
    • DanielD's Avatar
      DanielD

      Just finished 7 weeks of chemotherapy and radiation. In couple of weeks I’m scheduled to begin a year of Imfinzi (Durvalumab) every two weeks. I have Stage 3A NSCLC and it’s my understanding this currently is pretty much protocol since Pacific Trials.

      You might in interested in recent article (December 2018) “Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC.”
      https://www.nejm.org/doi/full/10.1056/NEJMoa1809697
      (You have to register with New England Journal of Medicine for access to full article. This gives you 3 free articles per month.)

      My understanding is that side effects of Imfinzi are tame compared with side effects of initial chemoradiation and that what side effects there are go a way in a couple of days of infusion.

      3 months ago
    • 2943's Avatar
      2943

      DanielD... ask about taking a Claritin (not D) for the first few days. I now take it daily due to itching. I am on Imfinzi (1down and 15 to go). Side effects much much less than chemo.

      3 months ago
    • 2943's Avatar
      2943

      That’s 11 down 15 to go!

      3 months ago
    • DanielD's Avatar
      DanielD

      2943... I'll ask about Claritin. Thanks for the tip! I'll keep you posted. Please do the same!

      3 months ago
    • 2943's Avatar
      2943

      DanielD...I started on Imfinzi 3 weeks post chemoradiation. Am also following Pacific protocol. Sooner you start the better. Hugs!

      3 months ago

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