The possible side effects are pretty much the same for both. The only difference is that Neupogen requires several injections (as many as 14) to provide the same infection prevention and one shot of Neulasta. I am on the pretty much the same regimen you are. I get bone achiness for for a couple of days from the neulasta. The other side effects I get are from the chemo (primarily Taxotere).
Invasive (Infiltrating) Ductal Carcinoma Questions
Neupogen better than Neulasta? related to side-effects?
Asked by cranburymom on Sunday, January 15, 2012
Neupogen better than Neulasta? related to side-effects?
One of patients @ infusion room told me that many of the side-effects I had been experiencing were coming from Neulasta, not from chemos (Taxotere, carboplatin). I had flu like symptoms and fever for 5 days, repeated night sweat (i meant totally soaked from neck to butt), pain along spinal and lower back especially hip area. Oh, yes nausea was always there but this is from chemo, I believe. It was a bit of surprise - did not even check the insert for Neulasta! My WBC is super high! this is also not so good, but at least I can continue my treatment. Anyone has similar experience?? Or good luck on Neupogen?
8 Answers from the Community
Hot flashes are a side effect of the chemo - your estrogen is dropping.... And that leads to chemopause.
Neulasta and neopogen are essentially telling your bone marrow to make infection fighting cells. The result can be high white cell counts, which I have had as well. No one seems to consider this a big deal.
The bone pain is bizarre. I have only gotten a tiny bit of it.... But those tiny bits hurts like craziness! My hip bones and my sternum hurt a ton, and if your heart rate is up when it is hurting, the pain seems to pulse with your pulse. Luckily for me, the total time in pain was maybe fifteen or twenty minutes total, spread over a few hours on day eight or nine after receiving the shot. I hear so me people get a more constant bone pain, and they find good relief with Tylenol or something similar.
Neulasta lasts ten days... One shot - ten days.... Versus neopogen, which lasts one day... And somehow, your bone marrow listens to neupogen and does not make much other stuff - other good stuff like red blood cells and platelets. All of my numbers seems to be better on neulasta than on neupogen. Now, that switch also coincided with a switch from the taxol / carboplatin to the ac step of my chemo because the former involved weekly treatments and the latter is every other week.
I hope this helps. The other tricky part is that some people get horrible joint pain with the tax style chemos.... I hope you are not so unlucky. I did not have much joint pain....
Also, I have written a bit about taking GLUTAMINE during chemo to prevent neuropathy and mouth sores. I can report that it is effective with regard to mouth sores. When I slacked off that supplement, I got mouth sores, and they are horrid horrid things. If you decide to use it, mix about ten grams in water.... And drink that slurry about three times per day.....
And hugs. Night sweats suck! Hot flashes suck! Chemo sucks!
Regarding fever - definitely ask your physician..... Fevers are tricky!
I had 5 shots of nuelasta during treatment and every time my bones ached and I was more physically ill than from just the chemo. I disliked it so much I tried to get out of the last one but my oncologist wouldn't let me. They informed me claritin might help with the side effects but I didn't try it. Good luck.
Hi Neighbor (we don't live far apart),
I had Neulasta and hated the side effects, but knew that I had to tolerate them in order to finish my chemo. I had severe achiness especially when I was jarred - i.e. our smoke detectors went off and my muscles stiffened. We are talking excruciating muscle spasms.
My oncologist only gave me the Neulasta every other treatment because my numbers were so high, but I was nervous each "off" cycle that my numbers would be too low the next round, but they weren't. That nasty stuff worked.
I did peruse some message boards and found that others recommended taking Claritin before the Neulasta shot. Try it...it did work for me and even my nurses said they had heard it worked.
Still having hot flashes...ob/gyn says the chemo probably shut down everything and that I'm probably in menopause (awaiting results from bloodwork).
Stay strong and positive!
Thank you all for great answers. I will try Claritin.
I have been taking Glutamine as often as I can (remember!). In addition to the benefit mentioned by Leepen, I understand that it prevented cancer from metastasizing in mice.
When feeling so tired and ill, I just want to quit the job and stay in a couch - then people like you all keep me going. So THANK YOU!
My friend dropped off amazing meals for me and my family. Feel like I can go out there with my new wig (hate it) and get through the week. I can do this, and I will.
Did you have any experience with Neupogen after you wrote this comment? My dad had Neulasta last time. I think the most painful part of that was looking at the $8,000/each price tag, times 4. This time around, they are going to use Neupogen. I have no experience with it, and wonder if he has to expect anything different.
I did not switch to neupogen, do I can't comment my experience.
But I heard that neupogen is better tolerated when compared to neulssta. One drawback can be the duration - neupogen stimulates White blood cells only for a short period - so one may need multiple injections. But I am not sure how true this is. I know people get neupogen. But I am not aware if they go back for many times more.
How much less you need to pay for neupogen?
&8,000 is huge. When I was receiving the radiation, I think that the cost was something like $3000x 30!!! This does not include doc's fees nor set up fees.
I can't afford to be a cancer patient!
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