• Off Hormone therapy and PSA is up

    Asked by lindi143 on Tuesday, October 17, 2017

    Off Hormone therapy and PSA is up

    My husbands PSA is up to 1.4 after being .04 after coming off the shots He has had radical prostate surgery and Chemo he was on the shots for almost 2 years and it kept it down I cant talk to dr until next week he is out of town anyone have any thoughts on this?

    13 Answers from the Community

    13 answers
    • barryboomer's Avatar
      barryboomer

      That just may be his normal without the Lupron which is a female hormone and that doesn't see too high....What kind of diet is he on?

      about 1 month ago
    • lindi143's Avatar
      lindi143

      He is eating lots of veggies and chicken he has lost weight and is exercising more. Thank you for the info he has just been off for 3 mos so this may be where it is gonna stay we will see. i just feel so much better when I talk to people here .

      about 1 month ago
    • davewfence's Avatar
      davewfence

      I know it does a person good to talk about it -- a lot of people who do not have this horrible disease or are touched by someone who does simply do not understand this

      about 1 month ago
    • Indyeastside's Avatar
      Indyeastside

      Not unusual. Will need to go back on Lupron. I have relapsed a few times. At some point might have to try another approach if Lupron proves to no longer work. Not worries waiting until doctor is back.

      about 1 month ago
    • lindi143's Avatar
      lindi143

      Thank Indyeastside and Davewfence for responding I appreciate it and it sure helps.

      about 1 month ago
    • barryboomer's Avatar
      barryboomer

      There is no specific normal or abnormal level of PSA in the blood. In the past, most doctors considered PSA levels of 4.0 ng/mL and lower as normal. Therefore, if a man had a PSA level above 4.0 ng/mL, doctors would often recommend a prostate biopsy to determine whether prostate cancer was present. He'd be much better eating only some fish like wild salmon. Chicken and Cows and Cows mile is not really people food.

      about 1 month ago
    • Whitey61's Avatar
      Whitey61

      Lindi143, here is my take, I'm a stage 4 Metastatic PC patient, your husband as already a PC patient, needs to have PSA monitored regularly, any variations from the normal of undetectable to even a slight elevation should be addressed as you will do shortly, HDT/Lupron is a female hormone that stops the production of male Testosterone by sending signals from the brain to the Testes, as you know this fuels the growth of Adenocarcinoma PC cells, his slight elevation could be the presence of prostate specific antigens in the bloodstream ie: cancer, or even infection , You mentioned he had chemo for any Metastatic systemic disease?, So I assume his cancer breached his prostate?, The thing to know is as part of his journey will be the need to take the injections to knock down the cancer cell division and keep it at bay, a slight rise in PSA is concern to a current patient, but maybe not as much to a guy without a diagnosis, but again, any rise from an undetectable to a 1.4 reading would warrant testing as this depending on age would change the risk factor.to give you an example, my Family has a Genetic DNA repair Gene defect for male's and PC...Dad, myself, then two brothers ages 48 and 52, had PSA,s done after my diagnosis...1.62 and 1.82 respectably, they would not have done anything if not for me and cancer was found in earliest stage for both of them, they both elected to have robotic removal and fine at moment, ...hope this helps, and his next HDT should knock it back down...best wishes

      about 1 month ago
    • lindi143's Avatar
      lindi143

      Whitey61 Thank you so much for explaining in laymans terms I have been trying to figure it out and what you said is the answer. This is just what I wanted to know. Thankyou again and best wishes for you and your family in the journey. I am trying to keep a positive outlook and not let this dominate but he is tested every three months sooooo it is with us allthe time. It just takes times to get used to the new normal.

      about 1 month ago
    • Whitey61's Avatar
      Whitey61

      Lindi143, yes, I live in 3 month blocks between Scans and bloodwork and just keep hope for the best news each time..it is a journey we are all on with our new normals...keep us posted.

      about 1 month ago
    • lindi143's Avatar
      lindi143

      Whitey61 Your story is alot like my husbands. Have you heard anything about immunology Therapy. The Chemo did such a job on my poor husbands feet i was wondering if the immunology would help if they suggest Chemo. I think they will do the Hormone treatment and may just keep him on it until somehting else happens. Still waiting to hear from the Dr. Thank you again you have been such a help.

      about 1 month ago
    • Whitey61's Avatar
      Whitey61

      Lini143, unfortunately for now there is no FDA approved Immunotherapy treatments for Prostate cancer, , I'm sure there are clinical trials ongoing you could have your Doctor research for you, I have an extremely rare form of it MPC with a POLE loaded mutation that qualified me for experimental checkpoint inhibitor's PD1/PDL1 Keytruda, but I don't express tumor PDL1 that makes it effective, it is working for me on a systemic approach at the molecular level, this is unprecedented treatment and I may be one of a kind in the world per research from my medical team, a female hormone cancer mutation only before seen in Uterine and Ovarian in woman showing up in a male Prostate Cancer Genetics...lucky me!

      27 days ago
    • lindi143's Avatar
      lindi143

      O my Whitey61 I sure hope it helps It sounds quite complicated but I am praying it will work. I think the dr is taking a lets wait and see if it goes up alot or if it will stay low without the shots.
      i dont know i feel i have to try and figure it out and i am just overwhlemed

      27 days ago
    • lindi143's Avatar
      lindi143

      Whitey61 do you see your oncologist as well as the urologist? we get the shots at the urologist and are now being sent back to the oncologist.

      27 days ago

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