• Opdivo for colon cancer?

    Asked by StegalMan on Wednesday, May 17, 2017

    Opdivo for colon cancer?

    I read this article that says Opdivo was given priority review for use in colon cancer back in the Spring. Has anyone here been given it for use for colon cancer, in a trial or otherwise?
    http://www.empr.com/drugs-in-the-pipeline/metastatic-crc-cancer-nivolumab-opdivo/article/649062/

    6 Answers from the Community

    6 answers
    • geekling's Avatar
      geekling

      Call the number on the page for information. It looks as though they are looking for clinical trial volunteers.

      If you meet their qualifications and you choose to give it a try, be aware that you are putting yourself onto a roulette wheel.
      Especially if it is a phase 1 trial.

      Choose carefully. Your life is on the line.
      What else are you doing to get rid of the cancer?

      2 months ago
    • LiveWithCancer's Avatar
      LiveWithCancer

      I joined a clinical trial for Opdivo nearly 4 years ago. It was just some numbers when I got into the trial - I didn't realize for quite some time that I was getting immunotherapy, much less know the brand name.

      For me, entering the trial was the best thing that could have ever happened. I thought I was joining for altruistic reasons - to help those coming along after me, but it has ended up extending my life for at least 4 years.

      But, not everyone responds like I did. The side effects can be devastating. So, like geekling says, it is a decision you have to carefully consider.

      Best of luck!!

      2 months ago
    • Skyemberr's Avatar
      Skyemberr

      I just went through chemo and surgery, etc for Colorectal cancer and during chemo my oncologist would not allow me to have neulasta , because he said he didn't feel that folfox should be mixed with it. He wouldn't even talk about opdivo. I think it's very new to usage in colon cancer, but it could be helpful? Are you in chemo right now, or trying to pick between opdivo and chemo?

      2 months ago
    • rdsd's Avatar
      rdsd

      My onc was considering it but it appears to only be working for those that have microsatellite instability (MSI). I am MSS (stable) and a majority of colon cancer patients are as well. ---

      2 months ago
    • geekling's Avatar
      geekling

      My goodness. I had to look up MSI & MSS. I must say I am a bit daunted that doctors are so quickly talking about genetic mutability when I am still against genetic modification of my food, nevermind my body.

      2 months ago
    • LiveWithCancer's Avatar
      LiveWithCancer

      Doctors are finding many specific treatments based on genetic mutations of the tumors. I knew lung cancer survivors should have their tumors tested for genetic mutations. I wasn't aware that it was important for other tumors as well. There are some drugs that work great for certain mutations and not at all against other mutations. It is awesome that researchers are discovering which drugs destroy or control which tumors. Targeted therapy drugs are usually way less destructive to the good cells and, therefore, are much easier on the patient.

      2 months ago

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