Socially! Every social sphere I used to play part in has been has modified to accommodate me, or moved away to ignore me. Basically, nothing is the same-- the conversations I have are different, the visual cues I receive are changed.. the select few that have not changed or gone away either were extremely close to begin with, or are disabled themselves.
Thus perspective has changed as well. Now that I have entered the kingdom of the sick, I realize that I had been ignoring it all this time. I'm now sitting on the periphery as able-bodied youngins walk by chatting zealously. People are afraid of being ill, I was afraid of being ill-- and now I no longer am afraid.
All of the people I used to ignorantly walk around-- the ones in the wheelchairs, with canes or colostomy bags-- I now know their stories and names. A lot has gone wrong since cancer came along, but this is one thing that turned out for the best, I think.