• R-CHOP, HIGH fevers,drenching sweats, very anemic, no infection ?

    Asked by janj on Friday, September 14, 2012

    R-CHOP, HIGH fevers,drenching sweats, very anemic, no infection ?

    Rick has Diffuse, Large B Cell Lymphoma. Two transfusions after chemo. Hgb at 7 and 8. Any ideas as to what is going on ? CLL/SLL Richter Transformation to DLBCL 6/2012 Has had 3 rounds of R-CHOP. Mini-Allo SCT after no evidence of disease.

    3 Answers from the Community

    • kiki95632's Avatar

      talk to your doctor. Rituxab will give you fevers and sweats. I took Beneydryl at home before treatment and they infused a bag before treatment. Stay hydrated even if you don't want to drink or eat. Keep your on eye on the goal, you getting better. It does get better...Good luck

      about 4 years ago
    • Harry's Avatar

      Rituxan is a chimera. That is, it contains both human and mouse proteins. Everyone has a reaction after their first treatment. Usually the reactions are reduced after subsequent treatments. My experience was much different with fairly mild reactions after my first treatment, a bigger reaction after my second, and anaphylactic shock after my third. But, I am unusual. Reactions are mild for most. Some have more serious reactions. I've never heard of anyone else whose reaction was as severe as mine.

      Definitly talk to your doctor about this. Pre-treatment with steriods and benedryl helps. So does slowing down the injection rate.

      I don't know about CHOP. I got bendamustine instead of CHOP. I believe CHOP causes reactions, too.

      about 4 years ago
    • lynndelee's Avatar

      I had CHOP 11 yrs ago, before Rituxan Was available. Very few side affects . 8 yrs later cancer came back in a differ form and the gave me RICE. That stuff made me lose my mind for 48 hrs. The first round..... No memory of the past, but they say I was happy! Sort of like I was drunk..... they gave me more of the blue stuff which made me tolerate my nex 5 rounds. It has been 22 yrs since my first diagnosis of Hodgkns!

      about 4 years ago

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