• Recurring ovarian cancer

    Asked by Junkadams on Saturday, April 20, 2019

    Recurring ovarian cancer

    Avastan and Doxil
    Side effects

    7 Answers from the Community

    7 answers
    • po18guy's Avatar

      Doxil: Mouth sores. Hand and foot syndrome.

      8 months ago
    • JaneA's Avatar

      I had very high blood pressure on Avastin along with a morning slight nose bleed. But the good news is that Avastin surely seemed to have worked well for me. I have been NED for almost 4 years. Best wishes.

      8 months ago
    • carm's Avatar

      Doxil will give you neuropathy and it is cardiotoxic so I'm sure they will get a baseline ejection fraction and once you have completed the therapy you will need another one done.

      8 months ago
    • Lynne-I-Am's Avatar

      Junkadams, I have not been on either of these drugs. I recommend watching the video by kalindria . She is a five year survivor ( almost six ) of ovarian cancer living with recurrence. I would also recommend leaving her a message on her wall. She had mouth sores and I think that was while she was in Doxil. I remember her getting a prescription from the doctor for Miracle Mouth Wash which helped relieve that discomfort. Today the thinking with many gyn/oncs, is to start ovarian cancer survivors on some kind of maintenance therapy for a time right after they finish frontline chemo to delay or possibly prevent a recurrence. Part of the new strategy is also combining two drugs together . In the past treatment for recurrences consisted of an either/ or approach. I know several women on Avastin . Although they have not reached NED on the drug, there has been no progression of their disease and they are busy living their lives. Of course everyone is different but there are many tools in the toolbox. Wishing you better days and success in your treatments.

      8 months ago
    • Julia52's Avatar

      Avastin: High blood pressure. I was put on high pressure medicine. One time 190/120 and had to go to ER. Bloody noses and sores in nose and sinus. I’m still dealing with sinus issues. In January I had a perforated bowel and had emergency surgery. 3 days in ICU and 2 days on a respirator. 8 days total. If you have had bowel surgery and mine was over a year prior, you have 2 to 3 percent change of a perforated bowel. I’m just on doxil now. I had mouth sores and blisters on my feet. The Magic mouthwash took care of the sores and during future infusions I iced my feet and chewed ice chips and used cream like bag balm on my feet. No more issues. It can damage your heart. (doxil). I have 2 more treatments. I have been told it is slow working. Will know in June if it worked.

      8 months ago
    • Lynne-I-Am's Avatar

      @Julia52, thanks for refreshing my memory- it is Magic Mouthwash .

      8 months ago
    • LiveWithCancer's Avatar

      I am sorry that you are facing a recurrence. I was on Avastin when I was first diagnosed and it made me very sick. I don't think it affects most people that way, but I experienced nausea, vomiting, constipation, and extreme fatigue. I didn't have the high blood pressure some do.

      I never took Doxil, but if that is the same as docetaxel, my first oncologist said it was harder on the body than the carboplatin I got at first. I chose to go into a clinical trial instead.

      Wishing you the best of luck.

      8 months ago

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