I don't think there has been any misunderstanding of your question Laureen. The answers you received from others on your previous thread provided the best answers they could give. When in treatment for cancer, it usually becomes difficult if not impossible to know which treatments are causing what side effects. In my case, I sometimes had side effect from a treatment within a day or two. Other times those side effects didn't show up until weeks or months after the treatment. I could give you a laundry list of side effects I've had at various times and with varying degrees of severity, but I can' t tell you with any certainty which side effects were the result of which drugs. Even if we could isolate that for you, the end result would be exactly what the manufacturers provide for each drug which is common and less common side effects experienced from that drug. The only difference is that with the manufacturer's information, it is based on thousands of reports making it far more statistically significant than the half dozen or so responses you will get to this post.
Endometrial (Uterine) Cancer Questions
Side effects of Doxil & Avastin, Part II Perhaps if I re-word my question, I will be better understood.
Asked by Laureen on Friday, January 11, 2013
Side effects of Doxil & Avastin, Part II
Perhaps if I re-word my question, I will be better understood.
We are all part of a virtual suppport group. The support group is together & I ask a general question: I'm going to be taking doxil & avastin together, has anyone else taken these, if so, what side effects did you experience or do you know someone who has taken these?
I know each person experiences different side effects, but if 5 people out of 9 have had constipation, I will know that constipation may be something I might get (or I might not).
I hope this helps you understand what I am looking for. Thanks
4 Answers from the Community
I am currently on Avastin. Had it along with my chemo of Carboplatin and Paclitaxel. The side effects I have from Avastin alone are: gum bleeding - not much, just two areas after eating crunchy or rough things and just for a minute or two, or after brushing my teeth even with a soft toothbrush. I continue to have a sensitive strip of taste buds down the middle of my tongue. Don't know if that is from Avastin or leftover from chemo. Finally every few weeks my joints HURT fora few days. helped by extra ibuprofen.
I was frightened to start Avastin, but found it to be no big deal. I am given benadryl 25 mg IV before the infusion.
I have had both Doxorubicin and Doxil - two forms of the parent drug Adriamycin - but both were in combination with six other drugs, so it is difficult to segregate the side effects. Doxil gave me some hand and foot syndrome and began attacking my skin in other areas toward the end. It was not pleasant at all, but effective medicine rarely is. My main concern with either of the drugs is heart damage. Some can occur immediately, and some can occur years later. However, research tends to show that if either drug is used in a saline IV (rather than being injected directly), it lessens the chances of heart damage. As well, Doxil itself is generally less toxic to the heart than Doxorubicin, since it has a liposomal coating and tends to be stored under the skin - which produces those skin reactions. As well, there is a lifetime max dosage of Adriamycin that one can receive, unless one's life is in immediate danger. In my case, I need not worry, as my lymphoma defeated both varieties and it will not be used again.