• Switching Aromatase Inhibitors

    Asked by nancyjac on Thursday, December 20, 2012

    Switching Aromatase Inhibitors

    I know a lot of you have switch from one aromatase inhibitor to another because of side effects. So far, I am managing ok with mine (Anastrazole) but I'm just curious.....when you switch to a different one, do you have to start all over again, or do you just pick up where you left off with the previous one? In other words, if you have taken AI 1 for say 15 months, and then switch to AI 2, do you have to take AI 2 for 5 years, or for 3 years, 9 months?

    6 Answers from the Community

    6 answers
    • debsweb18's Avatar

      I've switched to Femara after 10 months on Arimidex, then to Aromasin after another 2 months. So far after 6 weeks my side effects are not near as bad. I'm taking them for a total of 7-8 years. It didn't start all over.

      about 7 years ago
    • karen1956's Avatar

      I've been on all 3 AI's and tamox....no starting over....just cumulative time.....I took Arimidex for 8 months...then Femara for one month, tamox 2 months.....couple week break then Aromasin for 2 1/2 years when I finally said enough is enough!!!! All total, I endured AI's for 3 1/2 years!!! BUT, now that I've been off of them for 2 years 9 months, if I went back on them, it would be starting over...

      about 7 years ago
    • lynn1950's Avatar

      A friend started on tamoxifen and when she switched to Arimidex, the oncologist started her time from the beginning.

      about 7 years ago
    • SandiD's Avatar

      I started with Arimidex, because of side effects, I switched to Aromasin, and now Femara. I am trying to find which has the least side effects for me. No starting over, 5 years total for me. This was suggested by my oncologist. Good luck!

      about 7 years ago
    • attypatty's Avatar

      Dear Nancyjac:
      The time on AIs is for all of them - so 5 years total. But now some studies have shown 10 years to be more effective in DFS and OS. My onc has already indicated to me that she may have me on for 10 years. I have been on all three - Arimidex was the worst for me, Aromasin the best (ie. the least side effects). But I had to switch to Femara because after 6 weeks, I developed an allergic reaction to the Aromsin - head to toe hives! There is a 4th alternative - a once a month shot. So far the Femara has been bearable, except for headaches and short term memory loss that really bothers me. Still, I can endure the SEs better than the cancer, so as always, we
      Fight On,

      about 7 years ago
    • speedy's Avatar

      I had to switch from Arimidex to Aromasin after 3 month. The pain was just to much.

      about 7 years ago

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