• Triple Negative-taking Tamoxifien

    Asked by Young30 on Monday, March 18, 2013

    Triple Negative-taking Tamoxifien

    I was diagonosed in 2011 with TNBC, had a double mas done. I went to MD Anderson to get a second opioin and the doc there put me on Tamoxifen 20MG a day. my estrogen when I had it done during my surgery was 7%, when they read it in Texas it was 15% which is still very low. So I'm wondering if anyboyd else is having the same issues. I asked my doctor here if it helps for me to keep taking it he said he cannot tell me that. There is side affects to taking the meds but with me being TNBC I just wonder if it helps.

    7 Answers from the Community

    7 answers
    • Ydnar2xer's Avatar

      I can't answer to your TNBC, but I took Tamoxifen for 5 years after my DCIS diagnosis and had few problems taking it. When my BC came back in August, my onc told me it "should never have happened" because I had had lumpectomy, 35X rads and the five years of Tamoxifen. But sometimes, who knows why these flukes (whoops, I almost typed that OTHER word that starts with f!) happen? He also told me that now "they" are saying women should take TEN YEARS of Tamoxifen v. five. You might want to talk to your doc about that--?

      over 3 years ago
    • Young30's Avatar

      Thanks Ydnar2xer. I did ask my doc and he said he cannot tell me one way or the other if it's helping me by taking the meds. He said I'm TN and there is no drugs I can take.

      over 3 years ago
    • nancyjac's Avatar

      I've never heard of anyone that is triple negative taking it. On the other hand, if by the 7 and 15% you are referring to the percentage of cells in a tissue sample that had estrogen receptors, then you are not really estrogen negative, just a low positive.

      over 3 years ago
    • carm's Avatar

      This article just came out today. I hope this helps answer your question, Carm RN.


      over 3 years ago
    • barbaraanne's Avatar

      I have TNBC and was told that there is no medication at this time that could help or would work towards fighting the cancer. I have heard good and bad things about Tamoxifien, (for patients who are positive) I wouldn't take it if it wasn't geared toward fighting my type of cancer, esp if the side effects aren't pleasant. But best of luck to you in whatever you decide to do.

      over 3 years ago
    • Nomadicme's Avatar

      If an oncologist at MD Anderson gave it to you, there's a good reason. Are you referring to % ER or PR positive cells? I'd say any percentage of malignant cells the Tamoxifen can stop from growing that's great.

      over 3 years ago
    • Young30's Avatar

      Submitted IHC slides show the tumor cells on the biopsy specimen are positive for estrogen receptor (15%, weak stain) and low positive
      progesterone receptor (5%, weak stain) and equivocal for Her2/neu (2+). The tumor cells show high proliferative index (Ki67: 60%)

      Here is my report! When it got read here in town, my estrogen receptor was 7%

      over 3 years ago

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