• What does a serum protein electrophoresis report tell you?

    Asked by MyelomaBeacon on Thursday, March 28, 2013

    What does a serum protein electrophoresis report tell you?

    Some of these reports are confusing, does anyone know what this is?

    2 Answers from the Community

    • nancyjac's Avatar

      Serum protein electrophoresis (SPEP) is a laboratory test that examines specific proteins in the blood called globulins. Electrophoresis is a laboratory technique in which the blood serum exposed to an electric current to separate the serum protein components into five major fractions by size and electrical charge: serum albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and gamma globulins. Table 2 on this website gives a very concise chart of the interpretations of the overs and unders of these fractions.


      over 5 years ago
    • SueRae1's Avatar

      If you are having issues understanding your reports, speak with and go over them with your oncology team.

      over 5 years ago

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