• What does it mean when a certain chemotherapy drug works for a few months and then stops working?

    Asked by StegalMan on Tuesday, April 2, 2013

    What does it mean when a certain chemotherapy drug works for a few months and then stops working?

    3 Answers from the Community

    • SueRae1's Avatar

      I've had that issue. It exactly what it means. The chemo worked on reducing your tumor, but it is now not responding to this treatment. This is normal, your oncology team should be letting you know what your next cause of treatment will. When they first started treating my for Kidney Cancer I was on Sutent (Sunitinib) which worked great for the, my first follow up scan showed that my lesions had shrunk dramatically, my second showed that the primary lesion grew a bit, so I was switched to Afintor (afinitor) which kept my lesions stable for 2 years. The only reason I was taken off of the Afintor is that my Breast Cancer Metastasized and this drug was not comparable with the TNBC treatment.

      over 3 years ago
    • CAS1's Avatar

      Cancer has a way of changing and mutating in order to "HIDE" from cancer treatments like chemo. So you need to try another until your cancer mutates or dies. There are drugs and othert treatment combinations that are in clinical trials to re start the cancer to be sensitive to the original Chemo again and its making really great progress..Plus sometimes the cancers on their own can become sensitive again to the original chemo.

      over 3 years ago
    • Peroll's Avatar

      As noted cancer has a tendency to be come resistant to chemo over time, it is sneaky like that. the good news is that there are several very good and different chemo regimes for colon cnacer that can be tried and retried over time and there are new ones being developed all of the tme. I am currently on a colon cancer chemo drug that was just approved by the FDA last fall and i have several others over my journey. I certainly hope you don't need any where near the number I have had to use but it is nce to know that they are there if you need them. Good Luck

      over 3 years ago

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