• What else can you take for nausea besides Compazine, Reglan, or Zofran?

    Asked by packerbacker on Friday, November 16, 2012

    What else can you take for nausea besides Compazine, Reglan, or Zofran?

    I take different combinations of them, and the nausea never completely goes away. I don't throw up a lot, although more lately (several times a week), but the constant nausea drives me nuts! I've taken Emend before chemo a couple times, unsure if that heped. I've taken Ativan along with the Compazine and either Reglan or Zofran, but that just made me nauseous and tired. I used to give Phenergan in the hospital to patients but I haven't seen that med around lately. My diet isn't the best, but it shouldn't be causing me all this nausea. Any other options people have used?

    21 Answers from the Community

    21 answers
    • nancyjac's Avatar

      I have to wonder if taking different combinations of nausea meds isn't part of the problem rather than a solution. I get very nauseous from anesthesia and they give me a scopolomine patch (same thing they use for motion sickness) and works like a charm for me.

      almost 4 years ago
    • Sugarshine's Avatar

      I have Ativan, phenergan, and scopalimine patches. Had severe problems with nausea the first 6 months, has calmed down a lot now. Was admitted to the hospital several times for nausea and vomiting. Still get nauseated but the vomiting has stopped.

      almost 4 years ago
    • Peroll's Avatar

      I get very nauseated at chemo and perfer Ativan because combined with the Benadryl they give me it puts me out so Isleep through the nausea. I have learned that everyone reacts differently so ask your Drs what else is available and what can safely be combined. If you keep at it you should find something that works.

      almost 4 years ago
    • FreeBird's Avatar

      People keep telling me about ginger for nausea, but I've never tried it.

      almost 4 years ago
    • Lirasgirl33's Avatar

      Do you take your meds every recomended # of hours or as needed. The thing with a lot of these meds is that if you are already experiencing nausea it takes longer for the meds to take effect. I would take Zofran every 8 hours. At the half way mark (4hrs), I would take Compazine. So I would always have an overlap of nausea meds. If that still didn't work then I would use Ativan. I didn't like to use the Ativan too much because it turned me into a glob of jelly. I'd be out, meaning passed out asleep or just plain out of it. I used the Ativan only before going to bed if I needed it. My doctor also prescribed Marinol. Thankfully my nausea got less severe so I didn't have to use it. Let your doctor know how you are taking the meds and if they aren't working, he/she will most likely prescribe something else for you.

      Nausea has been one of the side effects that has been more constant throughout my treatment. I've just learned to deal with it. Oh, and also, make sure you eat on schedule. Having an empty stomach makes the nausea even worse. Even if you can't hold solids down, drink an Ensure or equivalent. Nutrition is very important while going through treatment. Ginger candy has also helped me. Try Ginger Chews from the Ginger People. They sell them at Trader Joe's I believe. This helps with mild nausea.

      almost 4 years ago
    • carm's Avatar

      There are other drugs like Aloxi, Emend, or Kytril that are the newer generation of antiemetics. Lorazepam is used as well. Peppermint also calms nausea if you wish to go the homeopathic route. Best of luck to you, Carm.

      almost 4 years ago
    • leepenn's Avatar

      Marinol is fantastic, but you do get high from it. So, if you don't mind (or like) being high, then that's a great drug to use. It's the active ingredient of marijuana...

      Emend helped me a lot. I also took the other's you mention - zofran and compazine etc...

      The nurses gave me great advice about scheduling the anti-nausea meds. For my last two cycles of chemo, I needed everything. For my last cycle of chemo, I ... uhm... didn't do so well. But, that was just one night. Anyway, the nurses said that tag teaming the anti-nausea drugs was the right approach. There were times when I had three or four active anti-nausea drugs in my system. As far as I know, that approach DOES NOT increase nausea.

      The key, they told me, is that you have to stay ahead of the nausea... Once your nauseous, it takes a lot more meds and time to get it back under control. For me, that was the first 3,4, or 5 days after the AC infusion days....

      I had a hard time eating enough - dropped a load of weight... Just zero interest. I had to remind myself to eat. But, when I did eat, it did help with the nausea.

      And ginger works. I drank it as tea.

      Sorry you're feeling so cruddy!

      almost 4 years ago
    • Linda2010's Avatar

      Anzemet 100 mg seemed to help my husband.

      almost 4 years ago
    • Linda2010's Avatar

      Forgot to mention that the pill lasts for 24 hours.

      almost 4 years ago
    • SueRae1's Avatar

      I was given a prescription for Emend - to take for the two days after my first infusion. I was fortunate that my nausea got bad enough for me to use it, but I have been told and have read good stuff about it. I have also used ginger tea and sucking candies which helps me cope with with chemo and non chemo related mild nausea and queasiness.

      almost 4 years ago
    • myb's Avatar

      I started chemo taking Zofran Premed IV (at the end of the IV, my hand coordination was horrible) and then Zofran pills at home, but was still nauseous and was very constipated by the end of the 46 hrs hooked up to chemo pump. My Onc switched me to Amend Premed IV and Ativan for nausea which worked much better for me.

      almost 4 years ago
    • ticklingcancer's Avatar

      You can still get Phenergan but for me, it didn't work as well as zofran. With My Oncologist, it wasn't necessarily a goal to keep the nausea at bay, although they did what they could. They didn't want me constantly throwing up. You have some good suggestions. Kytril is one they gave me before treatment and I believe it's avaliable in pill form. Sancuso is another one I tried. It's a patch so you're getting a slow dose of meds all day. I think it's a 7 day patch. I also had quite a bit of success with Anzemet. I hope one these proves to be helpful to you. Lets us know what your Doctor decides to try out on you. Hope you feel better!!!

      almost 4 years ago
    • NanHope's Avatar

      Ativan! Worked the best for me, by far.

      almost 4 years ago
    • SpunkyS's Avatar

      Check with your MD first. I am told that Milk Thistle tea, available from a general nutrition store or health market is very effective.

      almost 4 years ago
    • GregP_WN's Avatar

      This is going to sound just like my Dad, but all you young "kids" crack me up. 24 years ago when I had chemo, they gave me one little white pill and claimed that if take this about an hour before you come to treatment and it will "help" with nausea. I took it, and then threw up for 4 hours after every treamtment, then slept for a day and half. ....Didn't have all these anti nausea meds that there are now.

      And yes, before anyone asks, I had to walk to treatment....in the snow.... and it was uphill in both directions...

      Thats for you Dad.

      almost 4 years ago
    • SpunkyS's Avatar

      for Greg: When I administered chemo 25+ years ago we gave Valium IV, and/or a wonderful old Brompton's cocktail. Overhydrated by IV, and then started chemo which ran overnight. Some oral compazine or phenergan by rectal insertion. Did not help much. We hated chemo nights almost as much as our patients who also walked uphill both ways.

      almost 4 years ago
    • Merri's Avatar

      If you can get medical marijuana, do so. I would never have believed it, but it absolutely works..
      I use edibles, they come in so many forms. Also, by Rx, Ondansetron. ODT

      almost 4 years ago
    • Merri's Avatar

      If you can get medical marijuana, do so. I never would have believed it until I tried it but it absolutely works. I used edibles. Also, by Rx, Ondansetron ODT

      almost 4 years ago
    • HeidiJo's Avatar

      I did take Ativan and Zofran, but I am easily nauseous to begin with, so I used some home remedies.
      I used Canada Dry Ginger Ale ( the only ginger ale with real ginger in it)
      Sea bands to combat nausea
      Ginger tea (ginger root shaved into hot tea)
      crystalized ginger
      These things can be found at the grocery store
      I found they helped a lot

      almost 4 years ago
    • frannorm's Avatar

      My husband chemo treatment last 3 days. Before each treatment he take 2 granisetron 1 mg, 2dexamethasone 4 mg, and at night he take the same pill. They are steroid . He never vomited and the last treatment is next week. The treatment is 6 treatments of 3 days . He also took prochlorperazine 5 mg . never vomited.

      over 3 years ago
    • cleon's Avatar

      how soon can i take ativan after taking compazine? compazine is not helping nauseous,just making me jittery

      over 2 years ago

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