• what is triple negative breast cancer

    Asked by Pinkhd on Monday, December 10, 2012

    what is triple negative breast cancer

    8 Answers from the Community

    8 answers
    • karen1956's Avatar

      Triple negative breast cancer means it is not fueled by estrogen (ER) or progesterin (PR) or the HER2 gene. People who are Triple negative do not take tamoxifen or Aromatase Inhibitors (AI's) nor do they take Herceptin. Hope this helps a little...

      over 8 years ago
    • carm's Avatar

      Hello, I am an oncology nurse and Karen is correct. Your malignancy is not hormone driven. Triple negative is negative for estrogen, progesterone, and human epidermal growth factor receptor#2 negative so your treatment would be the standard chemo and not drugs that decrease your hormone level. Hope this helps, Carm.

      over 8 years ago
    • Ajfunstuff's Avatar

      If you haven't already done so, get your last will and testiment and living will in order.

      over 8 years ago
    • Sugarshine's Avatar

      It's not a bad idea to get your paperwork in order, but as a Nurse I tell everyone that. Anything could happen, as everyone says. Here's always the proverbial bus that could hit you. I was diagnosed over a year ago with stage IV pancreatic cancer. I was supposed to be dead before the year was out, as you can see I am not. Actually doing much better ;-). No one knows exactly how someone will react to treatment and there are new treatments and clinical trials everyday. Most of us just take one day at a time. No one is assured of tomorrow whether they have cancer or not. Best wishes for you as you go through this.

      over 8 years ago
    • leepenn's Avatar

      there's both an upside and a downside to triple negative.
      an upside is that we don't have to face long term medications with long term side effects.
      the downside is that we don't have the option of long term medications that can reduce our risk of recurrence.

      triple negative breast cancer - that's what i had. i did chemotherapy followed by a double mastectomy. so far, so good. as far as i know (and hope), i am cancer-free. i was able to get into a clinical trial, and i had a pretty tough chemo regimen. but, i had a complete pathological response, which reduces the risk of recurrence drastically.

      ask your health care team to explain everything to you. they should be able answer your questions, and if you are confused, they should be able to explain it again...

      if you end up having chemotherapy, consider using glutamine as a supplement - 10 g swirled in water three times per day for the first few days after each chemo treatment. it helps with neuropathy and some other side effects - even been tested in clinical trial. of course, talk to your docs about any supplements you are considering, but this one was strongly supported by my health care team.

      let's see - what else. i'm so sorry that you have this diagnosis. it is scary... but it does respond to chemotherapy...

      what's your treatment plan?

      good luck...

      over 8 years ago
    • Nomadicme's Avatar

      As per the response of others, triple negative means it's Her2 negative, PR negative, and ER negative. Those are all receptors found on the Breast Cancer cells that help the cell to grow. Her2 used to be associated with a poor prognosis, as it means the cancer is more aggressive. With the availability of Herceptin and other drugs targetting Her2 the prognosis is much better. Having one or all 3 of those receptors these days means that there are ways of targetting cancers that have those receptors - Herceptin and Tamoxifen/AIs (for the ER/PR).
      A cancer being triple negative means that the extra drugs now available in the breast cancer armamentarium are not available to fight for a triple negative. You're confined to the standard chemotherapy regimens. As with all cancers, the lower your Stage at diagnosis, the better your prognosis. Just because you're triple negative doesn't mean you're finished. Plus, as triple negative cancers have shown to be quite aggressive, there is a lot of research ongoing in this area.

      over 8 years ago
    • SueRae1's Avatar

      I am being treated for metastasized triple negative breast cancer - My last two MRIs showed that the lesion on my liver is shrinking, my latest bone scan came back normal, and all my markers are normal as well.

      over 8 years ago
    • ConnieB's Avatar

      @ Ajfunstuff, I don't think comments like yours are helping any of us that are trying to maintain our positive attitudes while going through a cancer journey. I believe a positive attitude has a lot to do with the recovery process. I wish you the best and will pray for you.

      over 8 years ago

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