• what is triple negative breast cancer?

    Asked by janeti on Thursday, January 3, 2013

    what is triple negative breast cancer?

    9 Answers from the Community

    9 answers
    • nancyjac's Avatar

      Triple negative means that the cancer is negative for HER2, estrogen, and progesterone, meaning that none of those hormones/enzymes are a factor in the growth of your cancer.

      over 4 years ago
    • karen1956's Avatar

      TNBC is cancer that is NOT fueled by estrogen, progesteron or HER2......people with TNBC don't take any meds after sugery/chemo/rads...

      over 4 years ago
    • SueRae1's Avatar

      The only thing I can add to the answers you have received, is that recent research has indicated that triple negative breast cancer acts like and responds to treatment more like ovarian cancer then they other types of breast cancer. Here's a link to an article that appeared late last year http://usatoday30.usatoday.com/news/nation/story/2012/09/23/genome-project-links-breast-and-ovarian-cancers/57831816/1 You may also want to check out the triple negative breast foundation http://www.tnbcfoundation.org/

      over 4 years ago
    • zappons' Avatar

      Hi, you might find it helpful to check out breastcancer.org site. It has tons of information and the forums are great for any questions you might have. :) Good luck

      over 4 years ago
    • SusanK's Avatar

      TNBC occurs less frequently; only 10-15% of breast cancers are triple negative. It is an aggressive cancer and the statistics are a little scary. However, more dollars are going to TNBC research these days, and my oncologist told me it can respond well to chemo. It more often affects African-American women in their thirties and forties. I am Caucasian and was sixty when I learned I had it. I have no family history of any kind of breast cancer.

      over 4 years ago
    • janeti's Avatar

      I think the problem is that ER and PR neg are also mentioned and her2

      over 4 years ago
    • smlisboa's Avatar

      Tnbc also only responds to chemo. I don't understand why some doctors have their patients do radiation treatments. If after 2 yrs of remission.....you are pretty much in the clear! I start doing my test of my blood fir cancer every 3 months for the next two years. Hopefully I will not have any reoccurrence.

      over 4 years ago
    • Michele's Avatar

      Hi Janeti,
      I have had triple negative breast cancer but instead of the hormone receptors HER2 Positive: Yes, ER Positive: Yes, PR Positive: the cancer is not affected by the female hormones. It doesn't care and estrogen will not effect it's growth. But it is a more virolent form of cancer which usualy grows more rapidly and the cancer cells them selves are more mutated and less resemble breast tissue. I have had my 4 months of chemo. the mastectomy and am now strting 5 1/2 weeks of radiation treatments. And I hope to be ready for reconstruction by early summer. I will see depending on the skin damage done by the radiation treaments. It's a chance I have to take. I hope this answered your question at least a little.


      over 4 years ago
    • GregP_WN's Avatar

      This is one of the links on our Diagnoses page to Triple Negative ductal breast cancer. If you click on the diagnoses tab at the top of the page, then enter the diagnoses you are looking for, you will get a page with lots of information, and on the left of that page will be any subtypes of that diagnoses.

      over 4 years ago

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