• What’s the difference between carcinoma in situ and invasive carcinoma?

    Asked by grannys on Thursday, December 20, 2012

    What’s the difference between carcinoma in situ and invasive carcinoma?

    I keep reading these different terms but cant seem to understand it

    3 Answers from the Community

    • nancyjac's Avatar

      In situ means in position or in place. In oncology it refers to malignant cells that have not passed through the basal lamina to any adjacent tissue (i.e. non invasive). Carcinoma in situ is synonymous with high-grade dysplasia in most organs. Invasive carcinoma, commonly called cancer, if left untreated, will invade and spread to surrounding tissues and structures.

      about 5 years ago
    • SueRae1's Avatar

      nancjac; you took the words right out of my mouth (as it were)

      about 5 years ago
    • carm's Avatar

      In situ means the cancer is confined within the walls of the organ or gland they originated in. They become malignant when they breach that border. Invasive is a cancer that breaks thru the original organ or gland and has spread to localized areas within close proximity. Metastasis is spreading beyondthe local area. Carm.

      about 5 years ago

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