I wanted to quit after my 8th round of FOLFOX, but I had a wonderful oncologist who kept me focused on the finish line. I finished in October 2011 and have just gotten my 2nd "cancer-free" scan results.
I didn't have the anal bleeding, but did have all the other side effects you experienced (including the horrible jaw pain) and severe chemo brain (memory loss and severe damage to my processing skills), permanent vestibular damage (balance), and nightmarish diarrhea after days and days of nightmarish constipation.
Some have resolved. Chemo brain is resolving slowly. I no longer feel embarrassed by my reduced processing skills - just got a new high-tech job and am confident that I will be successful. I can feel my hands and have about 90% of my fine motor skills. Feet are still numb. I am in PT for my balance issues and muscular and nerve damage. That damage caused drop foot which resulted in breaking toes on two separate occasions. I've been in a soft walking boot since May. It's frustrating, but I've accepted that "it ain't over when it's over." But it was all a small price to pay to gain 40+ years with my family and friends.