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    Angelina05 asked a questionThyroid Cancer

    Antibodies causing false thyroid levels

    • nancyjac's Avatar
      nancyjac

      I've been on synthroid of about 8 years now. The first 3 years were periodic increases in dosage and then stabilized for a while but now going through that process again since last year. I've had multiple test for TSH, T4, T3, and antibodies tests. However, the antibodies test does not have to do with you TSH level but rather to determine the cause of hypothyroidism. Hypothyroidism caused by destruction of thyroid function from these antibodies is called auto-immune thyroiditis or Hasimoto's thyroiditis. Cancer really doesn't have anything to do with it. Many people with auto-immune thyroiditis have never had cancer. Maybe your doctor is talking about different antibodies, but I've never heard of them causing errors in measuring TSH and it just doesn't seem logical to me that it could. However, it does make sense to me that the presence of some cancer antibody could be temporary based on your cancer or your treatment for it, and that could account for changes in your TSH levels but they would still be accurate for the time at which the blood was drawn.

      over 4 years ago
    • polytechnic's Avatar
      polytechnic

      An anti-TSH antibody can attach to TSH and form a complex called macro-TSH. That indeed can interfere with TSH blood tests. I think that some methods of testing are better insulated from this than others. But you need more knowledge than I have to find out which, etc.

      However you need to be aware that there can also be antibodies to T4 and to T3, as well as the 'usual' thyroglobulin and thyroid peroxidase.

      And it may be important to realise that the antibodies themselves do not attack things. TPOab and TGab are indicative of attack on a thyroid by, usually, autoimmune processes. But they can also appear transiently after neck injury (surgery or strangulation) and in those cases will usually reduce over time.

      over 4 years ago
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    Angelina05 shared an experience

    Radiation (Internal radiation): My second round of radiation came after my 3rd surgery. I again had to follow the low iodine diet and was in isolation for a few days after treatment.

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    Oh No (Cancer is back/Recurred ): My third recurrance was in July of 2005, the cancer had spread to my vocal cords. The doctor scraped off what he safely could without permantely harming my voice. I remember being so horse for weeks after my last surgery. Recovering was worse this time around. I was so sore and in a lot of pain. I had numbness in my neck/shoulder area for a while afterwards. I asked the doctor about it and he said it was from the trauma to that area.

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    Oh No (Cancer is back/Recurred ): my first recurrances was in Decem. 2004. I had another surgery to remove lymph nodes and glands that the cancer had spread to.

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    Angelina05 shared an experience

    Loss (Lost loved one): My grandmother, who had battled both breast cancer and liver cancer, died in August of 2005....a month after my 3rd and last surgery. She was my hero in every sense of the word. She knew, firsthand, what I was going through. Watching her succumb to this disease was heartbreaking.