Christine - her doctor may want to give her a stronger anti-nausea medication. Is she taking Zofran or something else? Zofran works fine for me with Temodar, but when I participated in a clinical trial that paired Temodar with an experimental drug, Zofran simply wasn't strong enough. I was given Kytril and Emend in combination. I hope that either she, or you as her advocate, can talk to her doctor about this issue.
I too had fatigue with both radiation and chemo, but they weren't done together. It sounds as if she has a double whammy going on. Praying for you both that she finds some resolution to these issues and is able to rest well.